| Round 22 | | Ajax | 0 |
| | Half-time: | 0-0 | | Referee: | Heynemann 6 | | Attendance: | 44,675 | | Possession: | 45%-55% | | Total shots: | 15-12 | | MoM: | Wendel | | TV: | highlights |
| | 88 Promes | | (4-3-3): Trapp 6½, Cuadrado 6, Denswil 7, Wendel 8, Veltman 7½, Fofana 6, Chiquinho 6, Promes 6½, Lucca 6, Danilo 5½, Furuhashi 6½ | | Celta Vigo | 0 |
| | 74 Diego Carlos | | (4-3-3): Adán 7½, Sergi Roberto 7½, Javi Galán 7½, David López 7½, Diego Carlos 7, Araujo 7 (55 Thiago Galhardo 6½), De La Torre 7, Sisto 6½, Gonçalo Paciência 6½, Gueye 7, Miguel Rodríguez 5½ | | Anderlecht | 2 | 29 Koopmeiners, 38 Longstaff | | Half-time: | 2-0 | | Referee: | Coué 7 | | Attendance: | 27,973 | | Possession: | 57%-43% | | Total shots: | 19-8 | | MoM: | Carlos Soler | | TV: | highlights |
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| | (4-3-3): Meret 7½, Geertruida 7½, Raum 7½, Longstaff 7, Koopmeiners 7, Le Normand 7½, Carlos Soler 8, Trossard 7½, Immobile 7½, Openda 5½, Gakpo 7 | | Lyon | 0 |
| | 2 Danilo, 37 Vanaken, 69 Turati | | (4-3-3): Turati 7, Dubois 6, Chilwell 6, Özcan 7½, Danilo 6½, Vanaken 6, Caqueret 6½, Ristic 6, Diallo 5½, Tousart 7½, Scarlett 5½ | | Borussia Dortmund | 0 |
| | Half-time: | 0-0 | | Referee: | Medina Cantalejo 6 | | Attendance: | 28,972 | | Possession: | 55%-45% | | Total shots: | 18-6 | | MoM: | Ito |
| | 34 Shaqiri | | (4-3-3): Bürki 6½, Toljan 8, Ito 8, Weigl 7, Lindelöf 7½, Balerdi 7½, Knauff 7½, Shaqiri 7½, Lázaro 7, Dahoud 6½, Azmoun 5½ | | West Ham United | 1 | 86 Benrahma | | 61 Hudson-Odoi | | (4-3-3): Vicente Guaita 7, Coufal 7, Digne 6 (87 Van Bergen 6), Král 6½, Diop 6½, Dawson 6½, Helinho 7, Benrahma 7, Hernández 7, Cullen 6½, Hudson-Odoi 5½ | | Everton | 1 | 73 Rondón | | Half-time: | 0-0 | | Referee: | Atkinson 7 | | Attendance: | 33,524 | | Possession: | 53%-47% | | Total shots: | 19-13 | | MoM: | Willock |
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| | (4-3-3): Hart 7½, Holgate 7 (74 Mina 6), Mykolenko 7½, Willock 8, Tarkowski 7½, Keane 6½, Bellegarde 6½, McNeil 6½, Rondón 6½ (74 Townsend 7), Doucouré 6, Maupay 7 | | Torino | 0 |
| | 59 Zappacosta | | (4-3-3): Milinkovic-Savic 8, Zappacosta 7, Vojvoda 6½, Mandragora 6½, Djidji 7, Kryvtsov 6½, Pussetto 6½, Álex Berenguer 7, Sanabria 6, Lukic 6½, Pellegri 6 | | Independiente | 1 | 1 Benedetto | | Half-time: | 1-0 | | Referee: | Halsey 6½ | | Attendance: | 40,176 | | Possession: | 44%-56% | | Total shots: | 12-14 | | MoM: | Rosier |
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| | (4-3-3): Campaña 6½, Rosier 8, Alonso 7½, Sottil 7, Pezzella 7, Martínez Quarta 6½, Vecchio 6½ (85 Kannemann 6), Cervi 7, Benedetto 6½, Sànchez Miño 6½, Meza 6½ | | Leicester City | 2 | 47 Iheanacho, 86 Ayoze |
| | (4-3-3): Ward 6, Aguilar 6½, Castagne 7, Gueye 7½, Amartey 7½, Phillips 6, Ayoze 6½, Barnes 6, Iheanacho 7, Mendy 6, Gray 6½ | | Lokomotiv | 4 | 3 Éder, 8 Golovin, 14 Miranchuk, 49 Sychev | | Half-time: | 3-2 | | Referee: | Tanner 5½ | | Attendance: | 27,586 | | Possession: | 55%-45% | | Total shots: | 14-11 | | MoM: | Denisov | | TV: | highlights |
| | 17 Miranchuk, 81 Magkeev | | (4-3-3): Guilherme 6, Jedvaj 7½, Denisov 8½, Miranchuk 6½, Bijol 6½, Magkeev 6½, Isidor 7, Golovin 7½, Éder 5 (69 Lebedenko 8), Smolov 6, Sychev 6½ | | Athletic Bilbao | 3 | 15 Muniain, 22 Guardado, 75 Muniain | | 57 Traoré | | (4-3-3): Agirrezabala 6½, Traoré 7½, Matviyenko 7, Taylor 7½, Núñez 7, Yeray 6½, Feghouli 7, Muniain 6½, Guruzeta 6½, Guardado 7, Diego 6 | | Marseille | 3 | 12 Sanson, 28 Ocampos, 89 Ocampos | | Half-time: | 2-0 | | Referee: | Kompany 9 | | Attendance: | 43,592 | | Possession: | 59%-41% | | Total shots: | 21-4 | | MoM: | Lirola |
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| | (4-3-3): Mandanda 7½, Lirola 8, Nuno Tavares 7½, Cabella 8, Gigot 7, Caleta-Car 5½ (64 Radonjic 7½), Sarr 7½, Ocampos 7½, Ayew 7½, Sanson 7, Sánchez 6 | | Atlético-MG | 0 |
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| | (4-3-3): Ustari 7, Guga 6½, Henrique 7, Soriano 6½, Murilo Cerqueira 6½, Maicon 6½, Róger 6½, Éverton Ribeiro 6½, Dodds 5½, Renato Augusto 6, Osvaldo 5½ | | Milan | 2 | 14 Zaccagni, 35 Origi | | Half-time: | 2-0 | | Referee: | Hansson 6 | | Attendance: | 44,248 | | Possession: | 48%-52% | | Total shots: | 11-7 | | MoM: | Alderete |
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| | (4-3-3): Diego López 7½, Umtiti 6½, Aina 7½, Bennacer 7, Kjær 8, Ely 6, Suso 6½, Zaccagni 8, Origi 7, Clasie 7, Niang 7½ | | Valencia | 0 |
| | 2 Maranhão, 9 Pepe, 72 Ilaix, 77 Foulquier | | (4-3-3): Romero 7½, Foulquier 6½, Alderete 8, Parejo 5½, Pepe 7, Gabriel Paulista 7, Ilaix 6½, Nani 6½ (47 Cenk 7), Maranhão 6½, Coquelin 6½, Rodrigo 7 | | Monaco | 1 | 5 Choupo-Moting | | Half-time: | 1-0 | | Referee: | Dondarini 7 | | Attendance: | 28,433 | | Possession: | 51%-49% | | Total shots: | 11-13 | | MoM: | Lecomte |
| | 51 Choupo-Moting | | (4-3-3): Lecomte 7½, Touré 6½, Boura 7, De Wit 6, Maripán 7, Glik 6½, Minamino 6½, Pepê 6½ (70 Rony Lopes 7), Choupo-Moting 6½, Adrien Silva 7½, Baldé 6½ | | Real Madrid | 0 |
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| | (4-3-3): Lunin 7, Nacho 7, Bernat 7, Vecino 7, Jesús Vallejo 7, Víctor 6½, Ramsey 6, Djuricic 6, Rafa Mir 6½, Mariano 6, Giovinco 6 | | Shakhtar | 3 | 35 Abraham, 58og Molinas, 80 Abraham | | Half-time: | 1-0 | | Referee: | Rosetti 5½ | | Attendance: | 45,468 | | Possession: | 51%-49% | | Total shots: | 12-6 | | MoM: | De Bruyne | | TV: | live |
| | 25 Okafor, 44 Shaw, 77 Elvedi | | (4-3-3): Lopes 6½, Calabria 7, Shaw 7, De Bruyne 8, Savic 7, Elvedi 6½, Brahim 7½, Martial 7, Abraham 7½, Zambo Anguissa 6½, Okafor 6½ | | Boca Juniors | 0 |
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| | (4-3-3): Rossi 7½, Zambrano 7½, Pelmard 7, Fernández 6½, Laporte 7½, Figal 6½, Molinas 7, Moi Gómez 6, Gigliotti 6½ (70 Weigandt 6), Vázquez 5, Villa 6½ | | Wolves | 2 | 6 João Gomes, 47 Hwang | | Half-time: | 1-1 | | Referee: | Faktor 7½ | | Attendance: | 30,710 | | Possession: | 51%-49% | | Total shots: | 17-10 | | MoM: | Alex Telles |
| | 18 Hoever, 31 Hélder Costa, 67 Saiss | | (4-3-3): José Sá 6½, Hoever 6, Kilman 7½, João Gomes 8, Davies 7, Saiss 6½, Fábio Vieira 7, Hwang 7, Corbeanu 6½, Hodge 6 (54 Campbell 5½), Hélder Costa 6 | | FC Porto | 1 | 36 Galeno | | 47 Oliver, 75 Aboubakar | | (4-3-3): Marcelo 6½, João Mário 7, Alex Telles 8, Stephen Eustáquio 6½ (82 Benassi 6), Cédric 6½, Livramento 6, Carrillo 7½, Galeno 7½, Aboubakar 6½, Oliver 6½, Taremi 6½ | | Round 23 | | Athletic Bilbao | 3 | 21 Guardado, 30 Feghouli, 84 Diego | | Half-time: | 2-0 | | Referee: | Clattenburg 7 | | Attendance: | 37,239 | | Possession: | 58%-42% | | Total shots: | 15-12 | | MoM: | Núñez |
| | 80 Yeray | | (4-3-3): Agirrezabala 8, Traoré 7½, Matviyenko 7, Taylor 8, Núñez 8½, Yeray 7, Feghouli 5½ (54 Iñigo Córdoba 7½), Muniain 7½, Guruzeta 6½ (68 Herrera 7½), Guardado 7, Diego 6½ | | Monaco | 0 |
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| | (4-3-3): Lecomte 8, Touré 6, Boura 6, De Wit 6½, Maripán 7 (58 Boussaid 6½), Glik 6, Minamino 6½, Pepê 6, Choupo-Moting 6½, Bayo 5½, Baldé 5½ | | Atlético-MG | 0 |
| | Half-time: | 0-0 | | Referee: | Circhetta 6½ | | Attendance: | 36,128 | | Possession: | 49%-51% | | Total shots: | 17-11 | | MoM: | Sottil |
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| | (4-3-3): Ustari 7½, Guga 6½, Henrique 7, Soriano 7, Murilo Cerqueira 8, Maicon 7, Róger 7, Éverton Ribeiro 7, Dodds 6, Renato Augusto 6½, Osvaldo 6 | | Independiente | 0 |
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| | (4-3-3): Campaña 8, Rosier 6½, Alonso 7½, Sottil 8, Pezzella 8, Martínez Quarta 6½, Vecchio 7 (85 Kannemann 6), Cervi 6½, Benedetto 6, Sànchez Miño 6½, Meza 6 | | Boca Juniors | 0 |
| | Half-time: | 0-1 | | Referee: | Gumienny 8 | | Attendance: | 46,830 | | Possession: | 51%-49% | | Total shots: | 14-16 | | MoM: | João Gomes |
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| | (4-3-3): Rossi 6½, Zambrano 6½, Pelmard 7, Fernández 7½, Laporte 7, Figal 6½, Molinas 7, Moi Gómez 7, Gigliotti 7, Vázquez 5½, Villa 7 | | Wolves | 1 | 9 Corbeanu | | 65 Corbeanu, 67 Saiss, 90+1 Hwang | | (4-3-3): José Sá 7½, Hoever 6½, Kilman 6½, João Gomes 7½, Davies 6½, Boly 6½, Fábio Vieira 6½ (73 Hélder Costa 7½), Hwang 6, Jiménez 7, Saiss 6, Corbeanu 6 | | Celta Vigo | 0 |
| | Half-time: | 0-1 | | Referee: | Øvrebø 7½ | | Attendance: | 32,723 | | Possession: | 43%-57% | | Total shots: | 14-9 | | MoM: | Javi Galán |
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| | (4-3-3): Adán 7, Sergi Roberto 6½, Javi Galán 8½, David López 8, Diego Carlos 6, Araujo 7 (63 Pineda 6), De La Torre 6½, Sisto 7, Gonçalo Paciência 6½, Gueye 6½, Miguel Rodríguez 5½ | | Lokomotiv | 1 | 37 Golovin | | 12 Jedvaj | | (4-3-3): Guilherme 7½, Jedvaj 7, Denisov 7, Miranchuk 7, Bijol 6½, Diveev 6½, Isidor 7, Golovin 6½, Smolov 7½, Éder 7 (52 Kruglov 7), Sychev 5½ | | FC Porto | 2 | 25 Stephen Eustáquio, 44 Carrillo | | Half-time: | 2-0 | | Referee: | Waddel 6½ | | Attendance: | 29,084 | | Possession: | 56%-44% | | Total shots: | 14-9 | | MoM: | Weigl |
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| | (4-3-3): Marcelo 6, João Mário 6 (66 Benassi 7½), Alex Telles 7, Stephen Eustáquio 6½, Oliver 6, Cédric 6, Carrillo 6½, Galeno 7, Aboubakar 6½, Grujic 7, Taremi 6 | | Borussia Dortmund | 2 | 60 Toljan, 90+2 Lázaro |
| | (4-3-3): Bürki 6, Toljan 7, Ito 7, Weigl 7½, Lindelöf 6½, Balerdi 6½, Knauff 7, Shaqiri 6½, Lázaro 6, Dahoud 6½, Azmoun 7 | | Leicester City | 1 | 3 Gray | | Half-time: | 1-1 | | Referee: | Onufer 5 | | Attendance: | 32,332 | | Possession: | 48%-52% | | Total shots: | 17-12 | | MoM: | Castagne |
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| | (4-3-3): Ward 6½, Aguilar 7, Castagne 7½, Gueye 6½, Amartey 7, Phillips 6, Ayoze 7, Barnes 6½, Iheanacho 7½, Mendy 6, Gray 5½ | | Shakhtar | 1 | 14 Brahim |
| | (4-3-3): Lopes 7, Calabria 7, Shaw 6½ (58 Fran Beltrán 7), De Bruyne 7, Savic 7½, Elvedi 6½, Brahim 7, Martial 6½, Abraham 7, Eriksen 6, Trincão 6 | | Lyon | 3 | 15 Caqueret, 43 Diallo, 89p Diallo | | Half-time: | 2-1 | | Referee: | Remy 7 | | Attendance: | 46,467 | | Possession: | 45%-55% | | Total shots: | 11-16 | | MoM: | Kjær |
| | 21 Ristic, 74 Lopy | | (4-3-3): Turati 7, Dubois 6, Chilwell 7½, Vanaken 6½, Danilo 6½, Assignon 5½ (54 Lopy 6), Özcan 6½, Ristic 6½, Diallo 6, Caqueret 6½, Scarlett 5½ | | Milan | 1 | 37 Suso | | 13 Niang, 41 Clasie | | (4-3-3): Diego López 7½, Umtiti 6½, Aina 7½, Bennacer 7, Kjær 8, Ely 6, Suso 7, Zaccagni 7½, Origi 7, Clasie 6, Niang 6½ | | Real Madrid | 2 | 19 Djuricic, 74 Rafa Mir | | Half-time: | 1-1 | | Referee: | Hauge 8 | | Attendance: | 33,163 | | Possession: | 44%-56% | | Total shots: | 20-9 | | MoM: | Vecino |
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| | (4-3-3): Lunin 6½, Nacho 6½, Bernat 6½, Vecino 7½, Jesús Vallejo 6½, Víctor 6, Ramsey 6½, Djuricic 6, Rafa Mir 6½, Mariano 5½, Giovinco 6 | | Ajax | 1 | 11 Promes | | 14 Fofana, 66 Promes | | (4-3-3): Trapp 7, Cuadrado 7, Denswil 7, Wendel 7, Veltman 7 (55 Dijks 7½), Fofana 6½, Grillitsch 7, Promes 7½, Lucca 7, Danilo 6½, Furuhashi 7 | | Torino | 1 | 80 Sanabria | | Half-time: | 0-1 | | Referee: | Piraux 6½ | | Attendance: | 27,962 | | Possession: | 55%-45% | | Total shots: | 18-12 | | MoM: | Mandragora |
| | 4 Kryvtsov | | (4-3-3): Milinkovic-Savic 5½, Zappacosta 7½, Vojvoda 7, Mandragora 8, Djidji 7, Kryvtsov 6½, Pussetto 7, Álex Berenguer 6½, Sanabria 7, Lukic 6, Pellegri 5½ | | Marseille | 3 | 21 Sanson, 48 Sánchez, 65 Sánchez |
| | (4-3-3): Mandanda 5½, Lirola 7, Nuno Tavares 6½, Cabella 6½, Gigot 6½, Caleta-Car 6, Sarr 6½ (46 Sakai 7), Ocampos 6½, Ayew 6½, Sanson 6½, Sánchez 6½ | | Valencia | 1 | 25 Coquelin | | Half-time: | 1-0 | | Referee: | Dowd 8 | | Attendance: | 45,492 | | Possession: | 53%-47% | | Total shots: | 11-16 | | MoM: | Pepe |
| | 25 Coquelin | | (4-3-3): Romero 6½, Foulquier 7, Alderete 7, Parejo 7½, Pepe 7½, Gabriel Paulista 6½, Ilaix 6, Nani 7½, Maranhão 6, Coquelin 6½, Rodrigo 7 | | Anderlecht | 0 |
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| | (4-3-3): Meret 7, Geertruida 7, Raum 6½, Guendouzi 7½, Koopmeiners 7, Dunk 6½, Carlos Soler 6½, Trossard 7, Immobile 7, Openda 6, Gakpo 6 | | West Ham United | 1 | 86 Obiang | | Half-time: | 0-0 | | Referee: | Mallus 10 | | Attendance: | 25,985 | | Possession: | 42%-58% | | Total shots: | 17-17 | | MoM: | Hart |
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| | (4-3-3): Vicente Guaita 7, Coufal 6½ (84 Cresswell 6), Emerson Palmieri 6, Lanzini 7½, Diop 6, Dawson 7, Helinho 7, Benrahma 7, Hernández 6, Obiang 6, Hudson-Odoi 5½ | | Everton | 1 | 48 Rondón | | 17 Doucouré, 50 Bellegarde, 75 Bellegarde | | (4-3-3): Hart 8, Jonny 7, Mykolenko 7½, Willock 7½, Tarkowski 6½, Mina 6, Doucouré 7, Bellegarde 7, Rondón 7, Doucouré 6, Maupay 6 |
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