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| Round 1 (22) Cagliari - Lens Everton - Besiktas FC Utrecht - Udinese Fiorentina - Anderlecht Hajduk Split - Belenenses Mallorca - Yokohama FMarinos Olympiakos - Dinamo Sassuolo - Leicester City Shakhtar - Bastia Torino - Club Brugge Vélez Sársfield - River Plate | Round 2 (23) Anderlecht - Vélez Sársfield Bastia - Torino Belenenses - Shakhtar Besiktas - Mallorca Club Brugge - Olympiakos Dinamo - Everton Leicester City - Fiorentina Lens - FC Utrecht River Plate - Sassuolo Udinese - Cagliari Yokohama FMarinos - Hajduk Split |
| Round 3 (24) Cagliari - Anderlecht Everton - Club Brugge FC Utrecht - Yokohama FMarinos Fiorentina - Belenenses Hajduk Split - Leicester City Mallorca - Dinamo Olympiakos - Bastia Sassuolo - Udinese Shakhtar - River Plate Torino - Lens Vélez Sársfield - Besiktas | Round 4 (25) Anderlecht - Sassuolo Bastia - Mallorca Belenenses - Vélez Sársfield Besiktas - Torino Club Brugge - Hajduk Split Dinamo - Shakhtar Leicester City - FC Utrecht Lens - Fiorentina River Plate - Everton Udinese - Olympiakos Yokohama FMarinos - Cagliari |
| Round 5 (26) Cagliari - Belenenses Everton - Lens FC Utrecht - River Plate Fiorentina - Yokohama FMarinos Hajduk Split - Besiktas Mallorca - Club Brugge Olympiakos - Leicester City Sassuolo - Bastia Shakhtar - Udinese Torino - Anderlecht Vélez Sársfield - Dinamo | Round 6 (27) Anderlecht - Lens Belenenses - River Plate Club Brugge - Besiktas Dinamo - Bastia Everton - Olympiakos FC Utrecht - Fiorentina Sassuolo - Cagliari Shakhtar - Hajduk Split Torino - Udinese Vélez Sársfield - Mallorca Yokohama FMarinos - Leicester City |
| Round 7 (28) Bastia - Club Brugge Besiktas - Dinamo Cagliari - FC Utrecht Fiorentina - Sassuolo Hajduk Split - Everton Leicester City - Torino Lens - Belenenses Mallorca - Shakhtar Olympiakos - Vélez Sársfield River Plate - Yokohama FMarinos Udinese - Anderlecht | Round 8 (29) Anderlecht - Besiktas Bastia - Fiorentina Cagliari - Mallorca Club Brugge - Dinamo FC Utrecht - Sassuolo Hajduk Split - Vélez Sársfield Leicester City - River Plate Lens - Udinese Shakhtar - Everton Torino - Olympiakos Yokohama FMarinos - Belenenses |
| Round 9 (30) Belenenses - Leicester City Besiktas - Bastia Dinamo - Anderlecht Everton - Torino Fiorentina - Cagliari Mallorca - Hajduk Split Olympiakos - FC Utrecht River Plate - Lens Sassuolo - Yokohama FMarinos Udinese - Club Brugge Vélez Sársfield - Shakhtar | Round 10 (31) Anderlecht - Club Brugge Belenenses - Olympiakos Cagliari - Everton FC Utrecht - Hajduk Split Fiorentina - Shakhtar Leicester City - Bastia Lens - Dinamo River Plate - Besiktas Sassuolo - Vélez Sársfield Udinese - Mallorca Yokohama FMarinos - Torino |
| Round 11 (32) Bastia - Lens Besiktas - Belenenses Club Brugge - FC Utrecht Dinamo - River Plate Everton - Leicester City Hajduk Split - Udinese Mallorca - Sassuolo Olympiakos - Yokohama FMarinos Shakhtar - Anderlecht Torino - Cagliari Vélez Sársfield - Fiorentina | Round 12 (33) Bastia - River Plate Besiktas - Yokohama FMarinos Club Brugge - Cagliari Dinamo - Leicester City Everton - Udinese Hajduk Split - Lens Mallorca - Fiorentina Olympiakos - Anderlecht Shakhtar - Sassuolo Torino - Belenenses Vélez Sársfield - FC Utrecht |
| Round 13 (34) Anderlecht - Hajduk Split Belenenses - Club Brugge Cagliari - Shakhtar FC Utrecht - Mallorca Fiorentina - Torino Leicester City - Besiktas Lens - Vélez Sársfield River Plate - Olympiakos Sassuolo - Everton Udinese - Bastia Yokohama FMarinos - Dinamo | Round 14 (35) Bastia - Yokohama FMarinos Besiktas - Cagliari Club Brugge - River Plate Dinamo - Udinese Everton - Belenenses Hajduk Split - Fiorentina Mallorca - Anderlecht Olympiakos - Sassuolo Shakhtar - Lens Torino - FC Utrecht Vélez Sársfield - Leicester City |
| Round 15 (36) Anderlecht - Bastia Belenenses - Dinamo Cagliari - Vélez Sársfield FC Utrecht - Shakhtar Fiorentina - Olympiakos Leicester City - Club Brugge Lens - Mallorca River Plate - Torino Sassuolo - Hajduk Split Udinese - Besiktas Yokohama FMarinos - Everton | Round 16 (37) Bastia - Belenenses Besiktas - Fiorentina Club Brugge - Yokohama FMarinos Dinamo - FC Utrecht Everton - Anderlecht Hajduk Split - Cagliari Mallorca - River Plate Olympiakos - Lens Shakhtar - Leicester City Torino - Sassuolo Vélez Sársfield - Udinese |
| Round 17 (38) Cagliari - Leicester City Everton - Bastia FC Utrecht - Anderlecht Fiorentina - Udinese Hajduk Split - River Plate Mallorca - Belenenses Olympiakos - Besiktas Sassuolo - Lens Shakhtar - Yokohama FMarinos Torino - Dinamo Vélez Sársfield - Club Brugge | Round 18 (39) Anderlecht - Belenenses Cagliari - Olympiakos FC Utrecht - Everton Fiorentina - River Plate Hajduk Split - Bastia Lens - Club Brugge Mallorca - Leicester City Sassuolo - Dinamo Shakhtar - Besiktas Udinese - Yokohama FMarinos Vélez Sársfield - Torino |
| Round 19 (40) Bastia - FC Utrecht Belenenses - Udinese Besiktas - Lens Club Brugge - Sassuolo Dinamo - Hajduk Split Everton - Fiorentina Leicester City - Anderlecht Olympiakos - Mallorca River Plate - Cagliari Torino - Shakhtar Yokohama FMarinos - Vélez Sársfield | Round 20 (41) Anderlecht - River Plate Cagliari - Bastia FC Utrecht - Besiktas Fiorentina - Dinamo Hajduk Split - Olympiakos Lens - Yokohama FMarinos Mallorca - Torino Sassuolo - Belenenses Shakhtar - Club Brugge Udinese - Leicester City Vélez Sársfield - Everton |
| Round 21 (42) Bastia - Vélez Sársfield Belenenses - FC Utrecht Besiktas - Sassuolo Club Brugge - Fiorentina Dinamo - Cagliari Everton - Mallorca Leicester City - Lens Olympiakos - Shakhtar River Plate - Udinese Torino - Hajduk Split Yokohama FMarinos - Anderlecht | |
| League rounds 22-42 (in brackets) are the respective return ties of rounds 1-21 above, i.e. round 42 is Anderlecht - Yokohama FMarinos, Cagliari - Dinamo etc. | |