| Round 42 | | Accrington Stan. | 5 | 27 Williams, 30 Barkley, 35 Rose, 54 Rose, 63 Zaha | | Half-time: | 3-0 | | Referee: | Bader 8 | | Attendance: | 31,049 | | Possession: | 58%-42% | | Total shots: | 22-8 | | MoM: | Chambers | | TV: | highlights |
| | 18 Rashford, 59 Cahill | | (4-3-3): Hart 8, Chambers 8, Rose 4½ (75 Jagielka 7½), Ramsey 7½, Cahill 7 (83 Shaw 6), Williams 7, Ward-Prowse 7½, Zaha 7½, Sturridge 7, Barkley 6½, Rashford 6 | | Milan | 0 |
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| | (4-3-3): Oblak 7, Aurier 6, Kolasinac 6½ (62 Joaquín 6), Linetty 6½, Javi Martínez 6½, Laporte 6, Volland 6, Mandzukic 6, Immobile 6½, Quintero 6, El Shaarawy 5½ | | Barcelona | 4 | 39 Suárez, 58 Iniesta, 78 Iniesta, 87 Maxwell | | Half-time: | 1-1 | | Referee: | Styles 7½ | | Attendance: | 63,462 | | Possession: | 57%-43% | | Total shots: | 21-12 | | MoM: | Maxwell | | TV: | live |
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| | (4-3-3): Casillas 7, Sergi Roberto 6½, Maxwell 8, Busquets 7½, Bartra 5 (84 Feghouli 6), Fernández 7, Dos Santos 7, Iniesta 7½, Suárez 7½, Gomez 6, Messi 7½ | | Ayr United | 1 | 31 McCarthy | | 22 Shawcross, 52 Long, 64 Fletcher | | (4-3-3): Butland 6½, Clyne 7 (83 Colback 6), Brunt 6 (82 Dawson 6), Fletcher 7, Shawcross 7, Dann 6, Davis 7, Townsend 6, Fletcher 6, McCarthy 6, Long 5½ | | Borussia Dortmund | 2 | 21 Aubameyang, 36 Hazard | | Half-time: | 2-0 | | Referee: | Knight 6 | | Attendance: | 42,685 | | Possession: | 48%-52% | | Total shots: | 11-20 | | MoM: | Dembélé |
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| | (4-3-3): Akinfeev 7½, Höwedes 7½, Schmelzer 6½, Bender 8, Papastathopoulos 8, Giménez 7½, Ginter 5½, Hazard 7½, Aubameyang 7½, Lavezzi 6½, Fekir 6 | | Anderlecht | 0 |
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| | (4-3-3): Proto 7½, Gillet 7, Pocognoli 7½, Dembélé 8, Wuytens 7, Ramis 6½, Marecek 7, Ilicevic 6½, Lukaku 7, Kerzhakov 7, Jonas 6 | | Chelsea | 1 | 84 Bellarabi | | Half-time: | 0-1 | | Referee: | Wieser 7 | | Attendance: | 50,224 | | Possession: | 50%-50% | | Total shots: | 5-15 | | MoM: | Perisic |
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| | (4-3-3): Muslera 6, Moses 6½ (59 Rafinha 6½), Baines 7½, Fabregas 6½ (70 Perisic 7½), Koulibaly 6½, Mustafi 6, Callejón 7, Pedro 6½, Llorente 7, Khedira 7, Bellarabi 6 | | Real Madrid | 3 | 2 De Rossi, 58 Ronaldo, 75 Ibrahimovic |
| | (4-3-3): Navas 6½, Sergio Ramos 7, Chiellini 7½, Kroos 6½, Piqué 7, Bonucci 6, Modric 6½ (62 Pepe 7), Ronaldo 7½, Ibrahimovic 6, De Rossi 6½, Bale 5½ | | Exeter City | 2 | 23 Keane, 62og Mendy | | Half-time: | 1-0 | | Referee: | Sedlacek 7½ | | Attendance: | 19,744 | | Possession: | 46%-54% | | Total shots: | 11-12 | | MoM: | Trippier |
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| | (4-3-3): Foster 7, Trippier 8, Milner 8, Barry 7, Keane 6½, Stephens 6½, Walcott 7, Redmond 7, Austin 6½, Delph 6 (67 Wisdom 7), Akpom 5½ | | Nantes | 1 | 61 Digne |
| | (4-3-3): Ruffier 7, Colin 6, Digne 7, Gonalons 7½, Mendy 7, Kurzawa 6½, Sissoko 6½, Griezmann 7, Jean 7 (72 Valbuena 6½), Di María 6½, Benzia 5½ | | FC Basel | 2 | 41 Enes, 62 Isco | | Half-time: | 1-2 | | Referee: | Ancion 5 | | Attendance: | 33,553 | | Possession: | 47%-53% | | Total shots: | 17-10 | | MoM: | Azpilicueta | | TV: | highlights |
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| | (4-3-3): Weidenfeller 6, Dani Alves 6½, Jordi Alba 7½, Matuidi 7, Sarr 6, Lichtsteiner 6, Florenzi 6 (62 Bernat 7), Isco 7½, Enes 7, Denis 6, Baldé 6½ | | Helsingborg | 2 | 8 Eriksen, 45 Sigurðsson |
| | (4-3-3): De Gea 6, Azpilicueta 8, Wendt 7, Sigurðsson 7½, Kjær 6, Christensen 6, Ekdal 7, Eriksen 7, Agüero 7, Diego Costa 6, King 6½ | | FC Porto | 2 | 5 Philippe Coutinho, 86 Philippe Coutinho | | Half-time: | 1-0 | | Referee: | Van Vliet 6 | | Attendance: | 45,127 | | Possession: | 59%-41% | | Total shots: | 17-15 | | MoM: | João Moutinho | | TV: | highlights |
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| | (4-3-3): Rui Patrício 7, Ricardo Esgaio 7, Alex Sandro 7½, João Moutinho 8, Miranda 8, Luisão 6 (79 Bruma 6), Marcelo 6, Philippe Coutinho 8, Falcao 7½, Otavio 6½, André Silva 7½ | | Lazio | 1 | 81 Radu | | 2 Ariaudo, 7 Ilicic, 27 Maurício | | (4-3-3): Berisha 6, Bonera 5½, Radu 7, Onazi 7 (81 Matri 6), Maurício 6, Ariaudo 6, Ziegler 6, Ilicic 6½, Defoe 6, Babacar 5½, Mertens 6 | | Liverpool | 2 | 3 Origi, 36 Origi | | Half-time: | 2-1 | | Referee: | Beschin 8 | | Attendance: | 30,644 | | Possession: | 55%-45% | | Total shots: | 20-10 | | MoM: | Vrsaljko |
| | 4 Wimmer, 36 Origi | | (4-3-3): Pyatov 7, Vrsaljko 7½, Sakho 7, Can 7, Wimmer 6½, Insúa 6, Henderson 6 (80 Pedro Chirivella 6), Valencic 6, Sørum 7½, Badelj 6½, Origi 5½ | | Ajax | 1 | 6p Milik |
| | (4-3-3): Zoet 7½, Veltman 7½, Willems 6, Ziyech 7, De Vrij 7, Viergever 7 (46 Kishna 6), Promes 7, Lens 6½, Milik 7, Huntelaar 6, Van Amersfoort 6 | | Newcastle United | 2 | 22 Götze, 41 Silva | | Half-time: | 2-1 | | Referee: | Bolognino 6½ | | Attendance: | 52,230 | | Possession: | 51%-49% | | Total shots: | 17-10 | | MoM: | Hummels |
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| | (4-3-3): Handanovic 7, Zabaleta 7½, Hummels 8, Vidal 7½, Godín 6 (82 Boëtius 6), Tah 6, De Bruyne 6½, Silva 6½, Higuaín 6½, Götze 7, Gayle 5½ | | São Paulo | 1 | 6 Diego |
| | (4-3-3): Hélton 7½, Maicon 6½, Wendell 7, Ganso 7½, Juan 7, Rodrigo Caio 5½, Renato Augusto 7, Lucas Moura 6½, Willian 6½, Diego 6½, Robinho 5½ | | Palermo | 1 | 20 Insigne | | Half-time: | 1-1 | | Referee: | Piraux 7 | | Attendance: | 38,975 | | Possession: | 47%-53% | | Total shots: | 15-14 | | MoM: | Petagna | | TV: | live |
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| | (4-3-3): Sommer 6½, Zappacosta 6½, Criscito 7, Parolo 7½, Astori 6½, Romagnoli 7, Candreva 6½, Insigne 7½, Petagna 7½, Bernardeschi 7, Vázquez 6½ | | Lille | 2 | 9 Valencia, 80og Parolo |
| | (4-3-3): Lloris 6½, Valencia 6½ (79 Tallo 6), Sidibé 6½, Thauvin 6½, David Luiz 7, Rodriguez 7, Gaitán 6, Lallana 6, Negredo 5½, Flamini 5½, Frey 6 | | Valencia | 1 | 35 Perotti | | Half-time: | 1-0 | | Referee: | Strampe 5½ | | Attendance: | 44,287 | | Possession: | 47%-53% | | Total shots: | 10-13 | | MoM: | Özil |
| | 9 Hernández, 89 Perotti, 90 Rafinha | | (4-3-3): Diego 6, Javi Manquillo 6½, Vargas 7, André Gomes 7½, Reyes 6, Aderlan 6, Santi Mina 6, Perotti 7, Hernández 6½ (61 Lennon 7½), Rafinha 5½, Rodrigo 6 | | Arsenal | 3 | 60 Marchisio, 72 Gibbs, 79 Sánchez |
| | (4-3-3): Buffon 6, Bellerín 7, Nacho Monreal 7, Özil 8, Koscielny 7½, Martins-Indi 7, Koke 7 (61 Gibbs 7½), Sánchez 7, Iwobi 6½, Marchisio 6½, Campbell 5½ | | Round 26 | | Ajax | 0 |
| | Half-time: | 0-1 | | Referee: | Kefalas 6½ | | Attendance: | 46,746 | | Possession: | 45%-55% | | Total shots: | 9-10 | | MoM: | Ramsey |
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| | (4-3-3): Zoet 6½, Veltman 6½, Willems 6½, Ziyech 6½, De Vrij 7, Viergever 7 (46 Kishna 7), Promes 7, Lens 7½, Milik 7, Huntelaar 6½, Van Amersfoort 6½ | | Accrington Stan. | 1 | 21 Zaha | | 12 Zaha, 87 Barkley | | (4-3-3): Hart 6½, Chambers 7, Rose 6½ (75 Jagielka 7), Ramsey 8, Cahill 7 (83 Shaw 6), Williams 6, Ward-Prowse 7½, Zaha 7½, Sturridge 6, Barkley 6, Rashford 6 | | São Paulo | 0 |
| | Half-time: | 0-2 | | Referee: | Reijgwart 6 | | Attendance: | 36,368 | | Possession: | 48%-52% | | Total shots: | 7-11 | | MoM: | Zappacosta |
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| | (4-3-3): Hélton 5, Maicon 7½, Wendell 7, Ganso 7, Juan 6½, Rodrigo Caio 6, Renato Augusto 7, Lucas Moura 6, Willian 7, Diego 6½, Robinho 6 | | Palermo | 3 | 15 Insigne, 38 Insigne, 60og Juan |
| | (4-3-3): Sommer 6, Zappacosta 7½, Criscito 7, Parolo 7½, Astori 7 (57 Destro 6½), Romagnoli 6½, Candreva 7, Insigne 7½, Petagna 6½, Bernardeschi 6, Vázquez 6½ | | Ayr United | 3 | 13 Long, 56 Fletcher, 80 McCarthy | | Half-time: | 1-1 | | Referee: | Rudy 7 | | Attendance: | 33,997 | | Possession: | 57%-43% | | Total shots: | 14-7 | | MoM: | Clyne |
| | 6 Cameron | | (4-3-3): Gordon 7, Clyne 7½, Brunt 6½ (57 Anya 7½), Fletcher 7½, Shawcross 7½, Cameron 6½, Davis 7, Townsend 7½, Fletcher 5½ (57 Watmore 7), McCarthy 7, Long 7 | | Chelsea | 1 | 34 Llorente |
| | (4-3-3): Muslera 6½, Moses 7, Baines 6½, Fabregas 6½, Koulibaly 7, Rüdiger 7 (57 Mustafi 6½), Callejón 7½, Pedro 6½, Llorente 6, Khedira 7, Bellarabi 5½ | | Round 32 | | Helsingborg | 2 | 25 Agüero, 60 Agüero | | Half-time: | 1-0 | | Referee: | José Pratas 6 | | Attendance: | 39,548 | | Possession: | 55%-45% | | Total shots: | 10-9 | | MoM: | Wendt |
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| | (4-3-3): De Gea 7, Azpilicueta 6 (60 Rojo 7), Wendt 8, Sigurðsson 7½, Kjær 7, Christensen 6, Ekdal 7½, Eriksen 7½, Agüero 7½, Diego Costa 6, King 6½ | | Lazio | 1 | 88 Bonera |
| | (4-3-3): Berisha 6, Bonera 7, Radu 7½, Onazi 6, Maurício 6½, Ariaudo 6½, Ziegler 5½, Ilicic 7, Defoe 6½, Babacar 6, Mertens 6½ |
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