| 0¹ | A lovely cross from GRAY was blasted goalbound by HØJLUND only for the Southampton 'keeper to claw away. |
| 7¹ | A penalty box meleé resulted in BARNES driving the ball wide. |
| 10¹ | NKUNKU flicked an easy chance past the near post. |
| 11¹ | DE KETELAERE shot over. |
| 19¹ | A header by KVARATSKHELIA at the near post was comfortably collected by the Colchester United 'keeper. |
| 22¹ | Uncertainty in the Colchester United defence enabled NKUNKU to hit an effort inches wide. |
| 23¹ | A shot from KVARATSKHELIA was booted off the line by WILLIAMS. |
| 26¹ | NKUNKU floated the ball to KVARATSKHELIA who turned it wide. |
| 26¹ | KONATÉ beat two Colchester United players and drove an effort inches wide. |
| 34¹ | KVARATSKHELIA's shot was well held by TRAPP. |
| 43¹ | A free-kick from DE KETELAERE raced inches over. |
| 0² | DE KETELAERE brought the ball away from JOÃO NEVES and stabbed a weak shot over the bar. |
| 11² | JOÃO NEVES headed over the bar. |
| 12² | A cross from BARNES left JOÃO NEVES in plenty of space but he snapped at his shot. |
| 14² | A twenty yard shot from GRAY caused the Southampton 'keeper little difficulty. |
| 19² | A fine dribble was ended by a good save by the oncoming TER STEGEN. |
| 24² | NKUNKU rushed through the Colchester United defence but shot straight at the 'keeper. |
| 26² | TER STEGEN dived to his right to save an accurate shot from Colchester United's HØJLUND. |
| 30² | A brilliant strike from KVARATSKHELIA was dealt with by a useful parry from the 'keeper. |
| 41² | A poor tackle gets GAKPO a yellow card. |
| 42² | SMIT was put clear by WEBSTER and he stepped inside the 'keeper but thrust his shot wide. |
| 44² | An exceptional effort from DE KETELAERE scraped the outside of the post. |