| Round 21 | | Blackburn Rovers | 1 | 71 Taddei | | Half-time: | 0-1 | | Referee: | Walton 6½ | | Attendance: | 31,259 | | Possession: | 44%-56% | | Total shots: | 8-18 | | MoM: | Carew |
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| | (4-4-2): Fielding 6, Garay 5½, Raúl García 6, Warnock 6½, Jarque 6, Ooijer 7, Taddei 6½, Tugay 7, Carew 7½, Busquets 5½, Alexandre Pato 6½ | | West Ham United | 2 | 22 Bojan, 85 Cissé | | 75 Bojan | | (4-3-3): Lehmann 6½, Michel Salgado 7, Wendell 7½, Denílson 7½, Gallas 7 (54 Fritz 7), Djourou 6½, Wright-Phillips 7½, Van Der Vaart 6½, Cissé 7, Bojan 7 (85 Stokes 6), Guti 7½ | | Chelsea | 3 | 14 Fernando Torres, 74 Fernando Torres, 76 Ronaldinho | | Half-time: | 1-1 | | Referee: | Marriner 6½ | | Attendance: | 42,505 | | Possession: | 57%-43% | | Total shots: | 15-10 | | MoM: | Puyol |
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| | (4-3-3): Cech 7, Cole 6½, Cole 7, Alex 5½ (51 Sneijder 7½), Terry 6½, Puyol 8, Ronaldinho 7½, Xabi Alonso 6, Fernando Torres 7, Messi 8, Pandev 7 | | Sheffield United | 1 | 18 Rooney |
| | (4-4-2): Coupet 6½, Ben Haim 7½, Chica 7, Petrov 6½, Bruno Alves 6½, Dragutinovic 6½, Nicolita 6½, Geovanni 6, Johnson 6½, Rooney 6½, Canella 6½ | | Everton | 3 | 46 Agüero, 60 Agüero, 61 Agüero | | Half-time: | 0-0 | | Referee: | Styles 8 | | Attendance: | 25,129 | | Possession: | 51%-49% | | Total shots: | 20-9 | | MoM: | Buffon | | TV: | highlights |
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| | (5-3-2): Buffon 8, Rafinha 6, Baines 7, Huddlestone 7½, Richards 7, Bonera 7, Diego 5½ (81 Kissock 6), Rodwell 7, Agüero 7½, Seedorf 7, Drogba 7 (86 Vaughan 6) | | Portsmouth | 0 |
| | 29 Boulahrouz | | (4-4-2): Frey 7½, Mathijsen 7½, Laursen 7, Boulahrouz 6, Bosingwa 7, Albelda 6½, Guardado 6, Muntari 6, Ballack 7, Defoe 6½ (76 Adriano 6), Klose 6½ | | Liverpool | 1 | 12 Silva | | Half-time: | 1-0 | | Referee: | Tanner 6 | | Attendance: | 45,172 | | Possession: | 52%-48% | | Total shots: | 15-14 | | MoM: | Jankulovski |
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| | (4-5-1): Reina 7, Maicon 7, Jankulovski 8½, Hamsyk 7, Demichelis 7, Carragher 7, Xavi 7, Silva 7½, Eto'o 7, Toulalan 6½, Robinho 7 | | Arsenal | 1 | 52 Adebayor |
| | (4-4-2): Almunia 6½, Lahm 5½, Chiellini 6½ (66 Higuaín 7), Mascherano 7, Sagna 6½, Clichy 6½, Gago 6½, Hleb 6½, Fabregas 6½, Van Persie 6½, Adebayor 5½ | | Manchester United | 1 | 21 Vílla | | Half-time: | 1-0 | | Referee: | Rennie 7½ | | Attendance: | 76,040 | | Possession: | 60%-40% | | Total shots: | 20-6 | | MoM: | Van Der Sar | | TV: | live |
| | 44 Ribéry, 60 Ferdinand | | (4-4-2): Casillas 7½, Sergio Ramos 8, Evrà 7½, Ferdinand 7½, Vidic 7, Cambiasso 7, Daniel 7½, Ribéry 7½, Vílla 7½, Berbatov 7, Cristiano Ronaldo 7 | | Newcastle United | 0 |
| | 4 Cannavaro, 41 Miguel | | (4-4-2): Van Der Sar 8, Zambrotta 6½, Kaladze 6½, Mikel 6½, Cannavaro 6, Kompany 6½, Miguel 6, Essien 6½, Henry 6½, Simão 6½, Montolivo 6½ | | Reading | 1 | 21 Shevchenko | | Half-time: | 1-1 | | Referee: | Riley 6 | | Attendance: | 12,012 | | Possession: | 44%-56% | | Total shots: | 9-12 | | MoM: | Lennon |
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| | (4-1-3-2): Stekelenburg 7, Rosenior 7½, Molinaro 6, Makélélé 7, Vermaelen 6½, Grygera 6, Beckham 6½, Hunt 7, Menez 7½, Shevchenko 6½, Vicente 6 | | Aston Villa | 1 | 45 Young | | 6 Young, 30 Lennon | | (4-3-2-1): Carson 7, Brown 6, Barry 7, Hargreaves 7, Lescott 7, Woodgate 6½, Diarra 7, Carrick 6½, Agbonlahor 7, Lennon 7½, Young 7 | | WBA | 1 | 51 Giovinco | | Half-time: | 0-0 | | Referee: | Webb 7 | | Attendance: | 27,929 | | Possession: | 44%-56% | | Total shots: | 10-13 | | MoM: | Gardner |
| | 26 Pires | | (4-4-2): Adler 7, Silvinho 6½, Cuéllar 6½, Alexis 6½, Albrechtsen 6½, Pires 6½, Vela 7, Marchisio 6, López 7, Khokhlov 7, Giovinco 6 | | Cardiff City | 1 | 77 Hreiðarsson |
| | (4-3-3): Green 7, Gardner 8, Hreiðarsson 7½, Bullard 7½, Nikl 7½, Bardsley 6½, Lauren 6½, Kewell 7½, Thompson 7, Quashie 5½, Kamarà 6½ | | Wigan Athletic | 2 | 48 Anelka, 67 Little | | Half-time: | 0-0 | | Referee: | Beeby 5½ | | Attendance: | 24,815 | | Possession: | 47%-53% | | Total shots: | 7-15 | | MoM: | Fernandinho | | TV: | highlights |
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| | (4-3-3): Nash 6½, Scharner 6½, Kilbane 6, Källström 7½, Delpierre 7½, Bramble 6½, Little 7, Koumas 7, Anelka 7, Heskey 6½, Cotterill 5½ | | Fulham | 2 | 47 Keane, 90 Keane |
| | (4-3-3): Akinfeev 6½, Westermann 7½, Berezutsky 6½, Córdoba 8, Ujfalusi 7½, Flamini 7, Lichtsteiner 7, Fernandinho 8½, Santa Cruz 7, Cahill 6½, Keane 6½ | | Round 22 | | Aston Villa | 1 | 19p Barry | | Half-time: | 1-1 | | Referee: | Atkinson 6½ | | Attendance: | 42,431 | | Possession: | 51%-49% | | Total shots: | 6-5 | | MoM: | Lescott |
| | 21 Carrick, 56 Lennon | | (3-1-3-3): Carson 7, Brown 8, Lescott 8½, Barry 7, Woodgate 6½, Hargreaves 7, Carrick 6½, Scholes 7½, Agbonlahor 5½, Lennon 7½, Young 6 | | Everton | 1 | 2 Drogba | | 61 Seedorf | | (5-3-2): Buffon 6½, Rafinha 7, Baines 7, Huddlestone 6½ (71 Kissock 7), Richards 6½, Bonera 7, Diego 6½, Rodwell 7 (71 Vaughan 6½), Agüero 6, Seedorf 7, Drogba 6½ | | Fulham | 1 | 29 Keane | | Half-time: | 1-0 | | Referee: | Halsey 7 | | Attendance: | 32,097 | | Possession: | 55%-45% | | Total shots: | 21-5 | | MoM: | Berezutsky | | TV: | highlights |
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| | (4-3-3): Akinfeev 8, Westermann 7½, Berezutsky 8, Córdoba 7½, Ujfalusi 8, Flamini 8, Lichtsteiner 7, Fernandinho 7½, Santa Cruz 7½, Cahill 6½, Keane 7½ | | WBA | 0 |
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| | (4-4-2): Adler 7½, Silvinho 6½, Cuéllar 6½, Alexis 6½, Albrechtsen 6, Pires 7, Vela 6½, Marchisio 7, López 7, Khokhlov 7½, Giovinco 6 | | Liverpool | 2 | 45 Eto'o, 61 Eto'o | | Half-time: | 1-1 | | Referee: | Taylor 6½ | | Attendance: | 45,359 | | Possession: | 55%-45% | | Total shots: | 18-13 | | MoM: | Jankulovski |
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| | (4-5-1): Reina 7, Maicon 7, Jankulovski 8½, Hamsyk 6, Demichelis 6½, Carragher 6½, Xavi 7, Silva 7, Eto'o 7, Toulalan 6, Robinho 6½ | | Manchester City | 1 | 26 Petrov | | 31 Leo Franco | | (3-5-2): Leo Franco 6½, Blaszczykowski 7, Lúcio 8, Perea 7, Gattuso 6½ (76 Mills 6), Milito 6½, Navas 7, Giggs 6½, Trezeguet 7, Gerrard 7, Petrov 6½ | | Portsmouth | 1 | 51og Bramble | | Half-time: | 0-0 | | Referee: | Haywood 6 | | Attendance: | 9,949 | | Possession: | 49%-51% | | Total shots: | 13-10 | | MoM: | Mathijsen |
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| | (4-4-2): Frey 7½, Mathijsen 8½, Laursen 7½, Boulahrouz 7½, Bosingwa 7, Albelda 7½, Guardado 6, Muntari 7, Ballack 7, Defoe 6½ (76 Adriano 6), Klose 7 | | Wigan Athletic | 0 |
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| | (4-3-3): Nash 8, Scharner 7, Kilbane 8, Källström 7, Delpierre 6½, Bramble 6, Little 7½, Koumas 6½, Anelka 7, Heskey 6½, Cotterill 5½ | | Reading | 2 | 8 Hunt, 29 Shevchenko | | Half-time: | 2-1 | | Referee: | Moss 7 | | Attendance: | 11,933 | | Possession: | 51%-49% | | Total shots: | 17-8 | | MoM: | Skrtel |
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| | (4-1-3-2): Stekelenburg 7, Rosenior 7½, Molinaro 7, Makélélé 7, Vermaelen 7, Grygera 6½, Beckham 7, Hunt 6, Menez 6 (76 Simunek 6), Shevchenko 7½, Vicente 7 | | Birmingham City | 1 | 14 Hitzlsperger |
| | (4-3-3): Given 7, Paulo Ferreira 8, Bridge 7½, Frings 7½, Skrtel 8, Éderson 6, Juninho 6½, Hitzlsperger 6½, Pavlyuchenko 6½, Crouch 6½, Zárate 6 | | Sheffield United | 2 | 20 Rooney, 21og Jarque | | Half-time: | 2-0 | | Referee: | Stamatopoulos 6½ | | Attendance: | 30,672 | | Possession: | 45%-55% | | Total shots: | 13-9 | | MoM: | Ooijer |
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| | (4-4-2): Coupet 6½, Ben Haim 7, Chica 7, Petrov 7½, Bruno Alves 7½, Dragutinovic 7, Nicolita 6½, Geovanni 6, Johnson 7, Rooney 7, Canella 6½ | | Blackburn Rovers | 1 | 74 Tugay |
| | (4-4-2): Fielding 6½, Garay 6½, Raúl García 7, Warnock 7, Jarque 6½, Ooijer 7½, Taddei 7½, Tugay 6½, Carew 7, Busquets 5½, Alexandre Pato 6 | | Tottenham Hotspur | 0 |
| | Half-time: | 0-1 | | Referee: | Boyeson 6½ | | Attendance: | 36,209 | | Possession: | 54%-46% | | Total shots: | 17-12 | | MoM: | Simons |
| | 89 Malouda, 90+2 Malouda | | (3-4-3): Víctor Valdés 7, Zaccardo 7½, Barzagli 6½, Marcos Senna 8, Dunne 7½, Ernst 6½, Del Piero 6½, Di Natale 6½, Toni 7½, Rakitic 6, Iniesta 7 (74 Malouda 6) | | Middlesbrough | 1 | 25 Olic |
| | (3-4-3): Timmer 7, Simons 8, Albín 6½, Oddo 7½, Fellaini 6½, Huth 6, Santacroce 6½, O'Neil 7, Tuncay 7, Cavenaghi 7, Olic 6½ | | West Ham United | 1 | 34 Cissé | | Half-time: | 1-2 | | Referee: | Vurens 5½ | | Attendance: | 34,406 | | Possession: | 39%-61% | | Total shots: | 11-14 | | MoM: | Daniel |
| | 15 Van Der Vaart, 25 Cissé, 90 Wright-Phillips | | (4-3-3): Lehmann 5½, Michel Salgado 7, Wendell 6½, Denílson 6½, Gallas 6, Djourou 7, Wright-Phillips 7, Van Der Vaart 6, Cissé 7, Bojan 6, Guti 6½ | | Manchester United | 2 | 37 Berbatov, 45 Berbatov | | 19 Sergio Ramos | | (4-4-2): Casillas 6, Sergio Ramos 7, Evrà 6½, Ferdinand 7½, Vidic 7, Cambiasso 7½, Daniel 8, Ribéry 7½, Vílla 7, Berbatov 7½, Cristiano Ronaldo 7 |
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