Crowd | | | Opponents |
| | | | | | | | | | | | | | | | | | | | | | | | | 40,946 | A | 2 (1) | Chelsea | L | 2-3 | 2-0 |
| 1 | 21 | 3 | 4 | 5 | 6b | 7 | 8s | 9b | 101 | 11 | 4 |
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| | 45,060 | H | 2 (2) | Arsenal | W | 2-1 | 1-1 | - -
| 1 | 2b | 3 | 4 | 5 | 6 | 7 | 81b | 91 | 10b | 11 |
| 4 |
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| | 44,710 | H | 2 (4) | Napoli | X | 2-2 | 0-2 | 0
| 1 | 2 | 3 | 4 | 5 | 6b | 7 | 81 | 91 | 10 | 11 |
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| | 33,849 | H | IS 1 | Rangers | W | 2-1 | 1-0 |
| 1b | 2 | 3 | 4 | 5 | 6b | 71 | 8 | 9 | 101 | 11 |
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| | 41,880 | H | WCT 1 {1} | Everton | X | 1-1 | 0-1 |
| 1 | 2 | 3 | 4 | 5b | 6 | 7 | 81 | 9 | 10 | 11 |
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| | 40,342 | A | 2 (5) | Aston Villa | L | 0-2 | 0-2 | 12
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| 2 | 3 |
| 5b | 6 | 7b | 8 | 9 | 4 |
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| 10b | 1 | 11 | 11 |
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| | 18,084 | A | 2 (3) | Lille | L | 0-2 | 0-1 | - -
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| 2 | 3 | 10 | 5 | 6 | 7 | 8 | 9 | 4 |
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| 1 | 11 | 4 |
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| | 33,698 | A | WCT 1 | Everton | L | 0-4 | 0-2 |
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| 2 | 3 | 10b | 5 | 6b | 7 | 8 | 9 | 4b |
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| 1 |
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| 11b | 4 |
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| | 22,961 | A | 2 (6) | Villarreal | X | 2-2 | 0-2 | 20
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| 2 | 3 | 10 | 5 | 6 | 7 | 81 | 9 | 4 |
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| 1 | 111 |
| 10 |
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| | 49,236 | H | 2 (7) | Torino | O | 0-0 | 0-0 | 19
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| 2 | 3 | 10 | 5 | 6b | 7 | 8 | 9b | 4 | 6 |
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| 1 | 11b |
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| | 29,138 | A | IS 2 | Parma³ | X | 1-1 | 0-1 |
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| 2 | 3 |
| 5b |
| 7 | 81 | 9 | 4 |
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| 6 | 1 |
| 10 | 11 |
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| | 36,768 | H | 2 (8) | Dundee United | W | 3-2 | 2-0 | 19
| 1 | 2 |
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| 5 |
| 71 | 8 | 92 | 4 | 4 |
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| 11 | 10 |
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| 3 | 6 | | 44,936 | A | 2 (9) | Sevilla | W | 2-1 | 0-1 | 14
| 1 | 2 |
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| 5b |
| 7 | 8 | 91 | 41 | 4 |
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| 11 | 10 |
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| 3 | 6 | | 49,283 | H | 2 (10) | FC Porto | X | 1-1 | 0-0 | 10
| 1 | 2 |
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| 7 | 8 | 9 | 4 |
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| 4 |
| 11 | 10 |
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| 31 | 6 | | 42,908 | A | 2 (11) | RB Leipzig | W | 2-0 | 2-0 | 11
| 1 | 2 |
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| 5 |
| 71 | 8 | 9 | 4 |
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| 4 |
| 11 | 101 |
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| 3 | 6 |
| A | 2 (12) | Manchester City |
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| H | 2 (13) | VfB Stuttgart |
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| A | 2 (14) | Sporting |
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| H | 2 (15) | Valencia |
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| A | 2 (16) | Sassuolo |
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| A | 2 (17) | FC Twente |
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| A | 2 (18) | Atalanta |
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| H | 2 (19) | Fiorentina |
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| A | 2 (20) | Spartak |
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| H | 2 (21) | Tottenham Hotspur |
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| H | 2 (22) | Chelsea |
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| A | 2 (23) | Arsenal |
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| H | 2 (24) | Lille |
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| A | 2 (25) | Napoli |
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| H | 2 (26) | Aston Villa |
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| H | 2 (27) | Villarreal |
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| A | 2 (28) | Torino |
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| A | 2 (29) | Dundee United |
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| H | 2 (30) | Sevilla |
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| A | 2 (31) | FC Porto |
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| H | 2 (32) | RB Leipzig |
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| H | 2 (33) | Manchester City |
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| A | 2 (34) | VfB Stuttgart |
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| H | 2 (35) | Sporting |
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| A | 2 (36) | Valencia |
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| H | 2 (37) | Sassuolo |
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| H | 2 (38) | FC Twente |
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| H | 2 (39) | Atalanta |
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| A | 2 (40) | Fiorentina |
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| H | 2 (41) | Spartak |
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| A | 2 (42) | Tottenham Hotspur |
| | Key: 2 - Division 2, {#} - leg number, (#) - league round number and ³ - away goals rule. |
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