| Round 5 | | Arsenal | 1 | 45 Clichy | | Half-time: | 1-1 | | Referee: | Bennett 6 | | Attendance: | 52,735 | | Possession: | 48%-52% | | Total shots: | 14-9 | | MoM: | Rosický |
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| | (4-4-2): Almunia 6, Touré 7½, Clichy 7, Albiol 8, Sagna 6½ (66 Bendtner 6), Gallas 6½, Hleb 7, Rosický 8, Van Persie 6½, Fabregas 6, Adebayor 7½ | | Blackburn Rovers | 1 | 38 Jarque |
| | (5-3-2): Friedel 6, Ooijer 7, Jarque 6, Warnock 6½, Nelsen 6, Emerton 6½, Bentley 7, Pedersen 6½, Santa Cruz 6½, Raúl García 7½, McCarthy 6 | | Aston Villa | 0 |
| | Half-time: | 0-0 | | Referee: | Durkin 8 | | Attendance: | 42,380 | | Possession: | 47%-53% | | Total shots: | 13-13 | | MoM: | Vidic | | TV: | live |
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| | (3-2-3-2): Carson 7, Brown 6½, Barry 6½, Hargreaves 6½, Woodgate 7, Reo-Coker 6½, Lennon 7½, Carrick 7½, Carew 7½, Agbonlahor 6½, Young 6½ | | Manchester United | 0 |
| | 8 Anderson | | (4-4-2): Van Der Sar 7½, Neville 7, Evrŕ 6½, Vidic 7½, Ferdinand 6½, Anderson 6½, Ribéry 6½, Scholes 7, Rooney 7½, Tévez 6, Cristiano Ronaldo 7 | | Chelsea | 4 | 20 Drogba, 28 Lampard, 42 Ronaldinho, 59 Wright-Phillips | | Half-time: | 3-1 | | Referee: | Gallagher 5½ | | Attendance: | 42,447 | | Possession: | 55%-45% | | Total shots: | 20-7 | | MoM: | Valencia | | TV: | highlights |
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| | (3-5-2): Cech 6½, Wright-Phillips 7, Alex 7, Essien 8, Terry 7, Ricardo Carvalho 7½, Ronaldinho 7, Cole 7, Drogba 6½, Lampard 7½, Ballack 6½ | | Wigan Athletic | 2 | 15 Sibierski, 70 Palacios |
| | (4-3-3): Kirkland 7, Scharner 7, Kilbane 6½, Bramble 6½, Boyce 7, Palacios 7, Valencia 8, Olembé 6½, Heskey 7, Sibierski 6½, King 6 | | Everton | 1 | 78 Yakubu | | Half-time: | 0-1 | | Referee: | Joslin 7 | | Attendance: | 40,480 | | Possession: | 54%-46% | | Total shots: | 14-15 | | MoM: | Agger |
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| | (4-2-2-2): Howard 6, Hibbert 6½, Lescott 6½, Carsley 6½ (61 Vaughan 7), Jagielka 7½, Bruno Alves 7, Neville 6, Pienaar 7, Yakubu 7, Cahill 7½, Johnson 6½ | | Liverpool | 2 | 44 Fernando Torres, 55 Babel |
| | (4-4-2): Reina 6, Finnan 7½, Agger 7½, Carragher 7, Skrtel 6, Mascherano 7½, Gerrard 7½, Riise 6½, Fernando Torres 7, Nasri 7, Babel 6 | | Fulham | 1 | 41 John | | Half-time: | 1-0 | | Referee: | Jones 6½ | | Attendance: | 22,014 | | Possession: | 51%-49% | | Total shots: | 10-14 | | MoM: | Ujfalusi |
| | 35 Bullard, 89 Seol | | (4-3-3): Niemi 7, Krřldrup 7½, Bocanegra 7½, Davis 7, Ujfalusi 8, Garay 6½, Smertin 7½, Seol 7, John 6, Bullard 6, Kamarŕ 6 | | Reading | 1 | 57 Shorey |
| | (4-1-3-2): Hahnemann 7½, Murty 7½, Shorey 7½, Makélélé 7½, Bikey 7, Sonko 6½, Beckham 7½, Harper 7, Doyle 6½, Shevchenko 6½, Hunt 7 | | Manchester City | 2 | 22 Vassell, 59 Elano | | Half-time: | 1-1 | | Referee: | Lodge 6½ | | Attendance: | 37,247 | | Possession: | 52%-48% | | Total shots: | 22-10 | | MoM: | Lúcio |
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| | (4-4-2): Isaksson 7, Richards 7½, Garrido 8, Fernandes 7, Lúcio 8, Dunne 7, Elano 7, Johnson 7½, Mwaruwari 7½, Vassell 6½, Castillo 6½ | | Derby County | 1 | 37 Villa | | 76 Savage | | (4-3-3): Adler 7, Dingsdag 8, Zuiverloon 6½, Gamberini 7, Dainelli 6½, Savage 6½, Pearson 7, Miller 7½, Teale 6½, Earnshaw 5½, Villa 6½ | | Portsmouth | 0 |
| | Half-time: | 0-1 | | Referee: | Poll 7½ | | Attendance: | 20,208 | | Possession: | 44%-56% | | Total shots: | 10-10 | | MoM: | Murphy |
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| | (4-3-3): James 7, Pamarot 7, Distin 7, Campbell 7, Johnson 7, Kranjcar 7, Muntari 6, Davis 6½, Defoe 6½, Adriano 7, Pedro Mendes 6½ | | Birmingham City | 1 | 11 Juninho | | 45 Bosingwa | | (4-4-2): McGregor 6½, Kelly 7, Murphy 8, Juninho 7, Ridgewell 7½, Jaďdi 6, Larsson 7½, Kapo 6½, Zárate 6½, Bosingwa 6½, McFadden 6 | | Sunderland | 1 | 4 Jones | | Half-time: | 1-1 | | Referee: | Wilkie 7 | | Attendance: | 40,087 | | Possession: | 40%-60% | | Total shots: | 10-11 | | MoM: | Taylor | | TV: | highlights |
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| | (4-1-3-2): Gordon 6, Halford 6, Higginbotham 6, Fellaini 7, Nosworthy 7, Bardsley 6½, Edwards 6, Montolivo 6½, Jones 6, Richardson 7, Connolly 6½ | | Newcastle United | 1 | 3 Milner |
| | (4-4-2): Given 6½, Daniel 8, N'Zogbia 7, Butt 7, Taylor 8, Rozehnal 6½, Geremi 7, Smith 7, Duff 6½, Owen 7, Milner 6½ | | Tottenham Hotspur | 3 | 5 Malbranque, 53 Keane, 74 Keane | | Half-time: | 1-1 | | Referee: | Reed 6½ | | Attendance: | 36,106 | | Possession: | 42%-58% | | Total shots: | 10-18 | | MoM: | Berbatov |
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| | (4-4-2): Robinson 6, Hutton 6½, Chimbonda 6, Boateng 7, Kaboul 7, Huddlestone 6½, Malbranque 6½, Gilberto 7, Berbatov 7½, Ghaly 6½, Keane 7 | | Middlesbrough | 2 | 31 Afonso Alves, 77 Afonso Alves |
| | (4-4-2): Schwarzer 6½, Young 7½, Arca 6½, Wheater 7, Taylor 6½, Pogatetz 7, O'Neil 7½, Boateng 7, Tuncay 6½, Cattermole 6, Afonso Alves 6½ | | West Ham United | 3 | 25 Noble, 58 Bellamy, 90+1 Upson | | Half-time: | 1-0 | | Referee: | Alcock 6½ | | Attendance: | 34,362 | | Possession: | 54%-46% | | Total shots: | 21-15 | | MoM: | Neill | | TV: | highlights |
| | 24 Etherington, 66 Bowyer, 79 Parker, 87 Bellamy, 90+2 Noble | | (4-4-2): Green 7½, Neill 8, Etherington 6, Parker 7, Upson 8, Ferdinand 6½, Faubert 7, Noble 7½, Ashton 7, Bellamy 6½, Boa Morte 5½ (61 Bowyer 7) | | Bolton Wanderers | 0 |
| | 44 Cole | | (4-3-3): Jääskeläinen 7, Steinsson 7, Taylor 6½, Nolan 6, Gabbidon 6½, Méité 6½, Diouf 6½, Davies 6, Cole 6½, Ljungberg 7, Vaz Té 6½ (66 Braaten 6) | | Round 4 | | Birmingham City | 2 | 54 Juninho, 64 Bosingwa | | Half-time: | 0-2 | | Referee: | Bates 6 | | Attendance: | 29,860 | | Possession: | 47%-53% | | Total shots: | 18-21 | | MoM: | Berbatov |
| | 45 Kapo, 86 Zárate | | (4-4-2): McGregor 6, Kelly 7, Murphy 6½, Juninho 7, Ridgewell 7, Jaďdi 6½, Larsson 7, Kapo 6½, Zárate 6, Bosingwa 6, McFadden 6 | | Tottenham Hotspur | 2 | 5p Berbatov, 42 Keane | | 11 Huddlestone | | (4-4-2): Robinson 7, Hutton 6, Chimbonda 7, Boateng 7½, Kaboul 7, Huddlestone 6, Malbranque 6, Gilberto 7, Berbatov 8, Ghaly 6, Keane 6½ |
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