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| Round 1 (22) Anderlecht - Torino Benfica - Athletic Bilbao Celtic - Dundee United Everton - Aberdeen FC Augsburg - Roma FC Basel - Parma Grêmio - Atlético Madrid Lille - Sassuolo Real Sociedad - AEK Udinese - Corinthians Vélez Sársfield - Zenit | Round 2 (23) AEK - FC Augsburg Aberdeen - Udinese Athletic Bilbao - Grêmio Atlético Madrid - Anderlecht Corinthians - Everton Dundee United - Vélez Sársfield Parma - Celtic Roma - Lille Sassuolo - FC Basel Torino - Benfica Zenit - Real Sociedad |
| Round 3 (24) Anderlecht - Parma Benfica - Corinthians Celtic - Sassuolo Everton - Atlético Madrid FC Augsburg - Aberdeen FC Basel - Roma Grêmio - Zenit Lille - AEK Real Sociedad - Torino Udinese - Dundee United Vélez Sársfield - Athletic Bilbao | Round 4 (25) AEK - Celtic Aberdeen - Grêmio Athletic Bilbao - Udinese Atlético Madrid - Benfica Corinthians - Lille Dundee United - Everton Parma - FC Augsburg Roma - Vélez Sársfield Sassuolo - Real Sociedad Torino - FC Basel Zenit - Anderlecht |
| Round 5 (26) Anderlecht - Sassuolo Benfica - AEK Celtic - Roma Everton - Zenit FC Augsburg - Atlético Madrid FC Basel - Aberdeen Grêmio - Dundee United Lille - Athletic Bilbao Real Sociedad - Corinthians Udinese - Torino Vélez Sársfield - Parma | Round 6 (27) Anderlecht - Celtic Atlético Madrid - Aberdeen Benfica - Everton Dundee United - Athletic Bilbao FC Augsburg - Corinthians FC Basel - Lille Real Sociedad - Vélez Sársfield Roma - Parma Sassuolo - AEK Udinese - Grêmio Zenit - Torino |
| Round 7 (28) AEK - Roma Aberdeen - Zenit Athletic Bilbao - FC Augsburg Celtic - Real Sociedad Corinthians - Atlético Madrid Everton - Udinese Grêmio - Benfica Lille - Anderlecht Parma - Sassuolo Torino - Dundee United Vélez Sársfield - FC Basel | Round 8 (29) AEK - Grêmio Aberdeen - Corinthians Athletic Bilbao - Torino Atlético Madrid - Parma Dundee United - Zenit Everton - Celtic FC Augsburg - Lille Real Sociedad - FC Basel Roma - Sassuolo Udinese - Benfica Vélez Sársfield - Anderlecht |
| Round 9 (30) Anderlecht - Real Sociedad Benfica - Dundee United Celtic - Vélez Sársfield Corinthians - Roma FC Basel - FC Augsburg Grêmio - Everton Lille - Udinese Parma - AEK Sassuolo - Atlético Madrid Torino - Aberdeen Zenit - Athletic Bilbao | Round 10 (31) Aberdeen - Sassuolo Athletic Bilbao - AEK Atlético Madrid - Roma Benfica - Anderlecht Corinthians - Celtic Dundee United - FC Augsburg Everton - FC Basel Grêmio - Real Sociedad Torino - Parma Udinese - Vélez Sársfield Zenit - Lille |
| Round 11 (32) AEK - Aberdeen Anderlecht - Grêmio Celtic - Benfica FC Augsburg - Everton FC Basel - Athletic Bilbao Lille - Dundee United Parma - Zenit Real Sociedad - Atlético Madrid Roma - Udinese Sassuolo - Torino Vélez Sársfield - Corinthians | Round 12 (33) AEK - Torino Anderlecht - Udinese Celtic - Grêmio FC Augsburg - Zenit FC Basel - Corinthians Lille - Atlético Madrid Parma - Dundee United Real Sociedad - Benfica Roma - Everton Sassuolo - Athletic Bilbao Vélez Sársfield - Aberdeen |
| Round 13 (34) Aberdeen - Anderlecht Athletic Bilbao - Parma Atlético Madrid - Vélez Sársfield Benfica - FC Basel Corinthians - AEK Dundee United - Sassuolo Everton - Real Sociedad Grêmio - FC Augsburg Torino - Lille Udinese - Celtic Zenit - Roma | Round 14 (35) AEK - Dundee United Anderlecht - Athletic Bilbao Celtic - Atlético Madrid FC Augsburg - Udinese FC Basel - Zenit Lille - Benfica Parma - Everton Real Sociedad - Aberdeen Roma - Torino Sassuolo - Corinthians Vélez Sársfield - Grêmio |
| Round 15 (36) Aberdeen - Celtic Athletic Bilbao - Roma Atlético Madrid - AEK Benfica - Vélez Sársfield Corinthians - Parma Dundee United - FC Basel Everton - Anderlecht Grêmio - Lille Torino - FC Augsburg Udinese - Real Sociedad Zenit - Sassuolo | Round 16 (37) AEK - Zenit Anderlecht - Corinthians Celtic - Torino FC Augsburg - Benfica FC Basel - Atlético Madrid Lille - Aberdeen Parma - Grêmio Real Sociedad - Athletic Bilbao Roma - Dundee United Sassuolo - Udinese Vélez Sársfield - Everton |
| Round 17 (38) Anderlecht - Roma Benfica - Aberdeen Celtic - Zenit Everton - Athletic Bilbao FC Augsburg - Sassuolo FC Basel - AEK Grêmio - Corinthians Lille - Parma Real Sociedad - Dundee United Udinese - Atlético Madrid Vélez Sársfield - Torino | Round 18 (39) Aberdeen - Roma Anderlecht - FC Augsburg Atlético Madrid - Zenit Benfica - Sassuolo Celtic - Athletic Bilbao Corinthians - Dundee United Everton - Lille Grêmio - Torino Real Sociedad - Parma Udinese - FC Basel Vélez Sársfield - AEK |
| Round 19 (40) AEK - Udinese Athletic Bilbao - Atlético Madrid Dundee United - Anderlecht FC Augsburg - Real Sociedad FC Basel - Grêmio Lille - Celtic Parma - Aberdeen Roma - Benfica Sassuolo - Vélez Sársfield Torino - Everton Zenit - Corinthians | Round 20 (41) Aberdeen - Dundee United Anderlecht - FC Basel Atlético Madrid - Torino Benfica - Zenit Celtic - FC Augsburg Corinthians - Athletic Bilbao Everton - AEK Grêmio - Sassuolo Real Sociedad - Roma Udinese - Parma Vélez Sársfield - Lille |
| Round 21 (42) AEK - Anderlecht Athletic Bilbao - Aberdeen Dundee United - Atlético Madrid FC Augsburg - Vélez Sársfield FC Basel - Celtic Lille - Real Sociedad Parma - Benfica Roma - Grêmio Sassuolo - Everton Torino - Corinthians Zenit - Udinese | |
| League rounds 22-42 (in brackets) are the respective return ties of rounds 1-21 above, i.e. round 42 is Aberdeen - Athletic Bilbao, Anderlecht - AEK etc. | |