| Round 42 | | Besiktas | 0 |
| | Half-time: | 0-0 | | Referee: | Dean 6½ | | Attendance: | 35,698 | | Possession: | 51%-49% | | Total shots: | 10-10 | | MoM: | Valencia |
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| | (4-3-3): Mert 7, Vida 7, Roco 6, Elneny 7½, Müldür 6½, Ravil 6, Douglas 6½, Semih 7, Aboubakar 6½, Salih 6½, Valencia 7½ | | VfL Wolfsburg | 0 |
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| | (4-3-3): Bushchan 7, Ryerson 7½, Fischer 6½, Arnold 7, Schlotterbeck 6½, Lacroix 6½, Gerhardt 6½, Victor Sá 7½, Strand Larsen 7, Paredes 6, Labeau Lascary 6½ (51 William 7) | | FC Utrecht | 1 | 45+2 Kerk | | Half-time: | 1-0 | | Referee: | Sarvan 6 | | Attendance: | 23,598 | | Possession: | 50%-50% | | Total shots: | 12-11 | | MoM: | Todibo |
| | 47 Hendriks, 75 Van Beek | | (4-3-3): Paes 6, Klaiber 7, Warmerdam 7½, Boussaid 7, Hendriks 6½, Van Beek 6½, Vlietinck 7, Kerk 7½, Lammers 7, Booth 7, Bahebeck 6 | | Lens | 2 | 56 El Ouazzani, 60 Loftus-Cheek |
| | (4-3-3): Turk 6, Cash 7, Lima 7½, Loftus-Cheek 7, Todibo 7½, Gradit 6½, Fortés 6½ (77 Nkoudou 6), Ikoné 6½, El Ouazzani 7½, Aubameyang 5½, Sotoca 7½ | | Hertha BSC Berlin | 2 | 25 Lazaro, 45+1 Süle | | Half-time: | 2-1 | | Referee: | Wieser 7½ | | Attendance: | 37,669 | | Possession: | 56%-44% | | Total shots: | 19-11 | | MoM: | Víctor Gómez |
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| | (4-3-3): Ospina 6½, Süle 7½, Lazaro 6 (85 Leckie 6), Duda 6½, Stark 7, Torunarigha 7½, Serdar 6½, Tolga 7½, Haller 6½, Selke 6, Undav 6½ | | Espanyol | 1 | 37 Calleri |
| | (4-3-3): O'Leary 6½, Víctor Gómez 8½, Miguel 7½, Vargas 6½, David López 6½, Tárrega 6, Wu 6, Adri Embarba 6½, Becker 6, Calleri 6½, Javi Puado 5½ | | Lazio | 2 | 17og Jefté, 72 Hysaj | | Half-time: | 1-0 | | Referee: | Dowd 6 | | Attendance: | 26,580 | | Possession: | 55%-45% | | Total shots: | 17-11 | | MoM: | Rovella |
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| | (4-3-3): Mandas 7½, Basic 6½, Hysaj 7½, Rovella 8, Provstgaard 6, Vecino 6½, Castellanos 7½, Zaccagni 7, Dia 7½, Isaksen 5½, Noslin 7 | | BATE | 0 |
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| | (4-3-3): Bellaarouch 7½, Isla 7½, Jefté 7, Lewis-Skelly 7, Magassa 7, Litvinov 6½, Durdov 7, Ljajic 6½, Miovski 6½, Batrakov 7, Ueda 6½ | | Leeds United | 1 | 35 Anthony | | Half-time: | 1-0 | | Referee: | Villadsen 9 | | Attendance: | 37,726 | | Possession: | 61%-39% | | Total shots: | 15-9 | | MoM: | Sánchez | | TV: | highlights |
| | 55 Rothwell | | (4-3-3): Dúbravka 7, Kristensen 8, Maatsen 8, O'Reilly 7, Sánchez 8½, Struijk 7½, Gruev 7, Anthony 7, Joseph 6½, Rothwell 6, Bamford 7 | | Hajduk Split | 1 | 64 Chakvetadze | | 21 Livaja, 32 Barisic, 90+2 Ivanovski | | (4-3-3): Kotarski 7, Juranovic 7, Barisic 6, Jradi 6, Sutalo 7, Bombito 6, Soticek 5½, Chakvetadze 7, Joselu 6, Ivanovski 5½, Livaja 6 | | Mallorca | 3 | 9 Álex Berenguer, 40 Álex Berenguer, 65 Álex Berenguer | | Half-time: | 2-0 | | Referee: | Knight 5½ | | Attendance: | 23,070 | | Possession: | 51%-49% | | Total shots: | 18-13 | | MoM: | Rajkovic |
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| | (4-3-3): Rajkovic 8, Adrià 7½, Diego Rico 7½, Mateus Fernandes 7½, Raillo 7, Latibeaudiere 6½, Manu 6, Álex Berenguer 5½ (84 Febas 6), Budimir 7, Abel Ruiz 6½, Lago Junior 6½ | | Auxerre | 0 |
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| | (4-3-3): Faríñez 7, Arcus 6½, Estupiñan 7½, Lees-Melou 7½, Bard 7, Kumbulla 6, Igor Gomes 6, Terrier 6½, Walter 6, Renato Sanches 6, Evanilson 6 | | Nice | 2 | 2 Mbeumo, 61 Koopmeiners | | Half-time: | 1-1 | | Referee: | Leonardo 5 | | Attendance: | 17,943 | | Possession: | 59%-41% | | Total shots: | 13-7 | | MoM: | Kerkez |
| | 9 Coman, 83 Guessand | | (4-2-3-1): Sánchez 6½, Gusto 7½, Kerkez 7½, Laimer 5½, Konsa 7½, Milenkovic 7, Rashford 6, Reijnders 7 (71 Rosario 7½), Mbeumo 6 (71 Guessand 6), Koopmeiners 7½, Coman 7 | | Ferencváros | 1 | 41 Rits | | 35 Buchanan | | (4-3-3): Dibusz 7, Murillo 7, Buchanan 6, Onyedika 7, Mechele 7, Clinton 6, Skov Olsen 7 (51 Meijer 6½), Abu Fani 6, Pesic 6, Rits 6, Stassin 5½ | | Olympiakos | 2 | 15 Bruma, 56 Bakambu | | Half-time: | 1-1 | | Referee: | Sedlacek 5½ | | Attendance: | 32,971 | | Possession: | 54%-46% | | Total shots: | 21-6 | | MoM: | El Hilali |
| | 56 Fortounis, 59 Bruma, 84 Camara | | (4-3-3): Tzolakis 6½, El Hilali 8, Hato 6½, Camara 7½, Semedo 6 (84 El Arabi 6), Emirhan 6½, Randjelovic 7, Bruma 7, Bakambu 6½, Fortounis 6, Sesko 7 | | Juventus | 1 | 31 Pavoletti |
| | (4-3-3): Cragno 7, Zappa 6½, Kostic 7½, Fagioli 7, Bisseck 6½, Ely 6, Man 7, Yildiz 6½, Pavoletti 7, Pellegrini 5½, Adams 5½ | | River Plate | 3 | 45+3 Varela, 49 Beltrán, 67 Solari | | Half-time: | 1-1 | | Referee: | Bettin 6 | | Attendance: | 50,883 | | Possession: | 51%-49% | | Total shots: | 15-17 | | MoM: | Denisov |
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| | (4-3-3): Kelleher 7, García 7, Funes Mori 7½, Varela 7½, Díaz 6½, Martínez 7½, De La Vega 6½, Solari 7½, Borré 6½, Palavecino 7, Beltrán 7 | | Lokomotiv | 1 | 40 Moumi | | 11 Kvirkvelia, 44 Zhemaletdinov | | (4-3-3): Guilherme 7, Nenakhov 6½, Denisov 8, Miranchuk 7, Vavro 8, Kvirkvelia 6, João Mário 6½, Moumi 6½, Glushenkov 6½, Smolov 6, Zhemaletdinov 6½ | | São Paulo | 2 | 18 De Jong, 40 Lázaro | | Half-time: | 2-0 | | Referee: | Constantin 7 | | Attendance: | 44,038 | | Possession: | 43%-57% | | Total shots: | 8-11 | | MoM: | McTominay |
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| | (4-3-3): Jandrei 6, Adams 6½, Angeliño 7, McTominay 8, Diego Carlos 7, Arboleda 6½, Ward-Prowse 6, Gabriel Teixeira 6½, De Jong 7½, Pablo Maia 6½, Lázaro 6 | | Dinamo | 1 | 88 Mostovoy | | 31 Mostovoy, 85 Varela | | (4-3-3): Akinfeev 7½, Varela 7, Skopintsev 7½, Okay 7½, Babic 7½, Balbuena 6½, Zakharyan 6, Mostovoy 7, Komlichenko 6½, Bakaev 6, Tyukavin 6 | | Vitória Guimarães | 1 | 38og Ordets | | Half-time: | 1-1 | | Referee: | Dinelli 7 | | Attendance: | 29,846 | | Possession: | 40%-60% | | Total shots: | 12-15 | | MoM: | Král | | TV: | live |
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| | (4-3-3): Varela 6½, Sánchez 6½, Matheus Reis 6, Bondarenko 6½, Zanka 7, Borevkovic 6, Kaio 7½, Tomás Händel 6½ (80 Nélson Oliveira 6), Banza 6, Arcanjo 6, André Silva 6 | | Shakhtar | 1 | 2 Sikan |
| | (4-3-3): Conde 7, João Mário 8, Rúben Vinagre 7½, Florentino Luís 6½, Tarkowski 6½, Ordets 6, Tetê 6½, Solomon 7½, Sikan 7½, Král 8, Colley 6 | | Round 31 | | Auxerre | 0 |
| | Half-time: | 0-0 | | Referee: | Racalbuto 5½ | | Attendance: | 19,983 | | Possession: | 51%-49% | | Total shots: | 9-16 | | MoM: | Lees-Melou |
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| | (4-3-3): Faríñez 7, Arcus 6½, Estupiñan 7, Lees-Melou 9, Bard 8½, Kumbulla 6½, Igor Gomes 6½, Terrier 7½, Walter 6½, Renato Sanches 6, Evanilson 6½ | | Vitória Guimarães | 1 | 70 Tomás Händel |
| | (4-3-3): Varela 7, Sánchez 6½, Matheus Reis 7½, Bondarenko 6½, Zanka 7½, Borevkovic 7, Kaio 7½, Tomás Händel 6½, Banza 7, Arcanjo 5½, André Silva 6½ | | Round 26 | | Juventus | 2 | 55og Sánchez, 73 Kostic | | Half-time: | 0-0 | | Referee: | Piraux 6½ | | Attendance: | 41,435 | | Possession: | 46%-54% | | Total shots: | 10-6 | | MoM: | Dúbravka |
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| | (4-3-3): Cragno 7½, Zappa 7, Kostic 7, Fagioli 6½, Bisseck 6, Ely 6½, Man 7, Yildiz 7, Pavoletti 7, Pellegrini 5½, Adams 5½ | | Leeds United | 0 |
| | 5 O'Reilly, 6 Dúbravka, 43 Rutter, 51 Joseph, 55 Struijk | | (4-3-3): Dúbravka 7½, Kristensen 6½, Maatsen 7½, O'Reilly 7½, Sánchez 7, Struijk 6½, Gruev 6½, Anthony 7, Rutter 6½, Joseph 5½, Bamford 6 | | Round 27 | | Mallorca | 2 | 4 Álex Berenguer, 55 Latibeaudiere | | Half-time: | 1-0 | | Referee: | Sandra 6½ | | Attendance: | 23,062 | | Possession: | 43%-57% | | Total shots: | 8-12 | | MoM: | Kerkez |
| | 6 Budimir, 41 Álex Berenguer, 55 Cucho, 57 Álex Berenguer, 76 Lago Junior | | (4-3-3): Rajkovic 6½, Adrià 6 (75 Abel Ruiz 6½), Diego Rico 7, Mateus Fernandes 7, Raillo 6½, Latibeaudiere 7, Manu 6, Álex Berenguer 7, Budimir 7, Cucho 6, Lago Junior 5½ | | Nice | 1 | 88 Konsa | | 1 Mbeumo, 7 Koopmeiners, 54 Reijnders | | (4-2-3-1): Sánchez 7, Gusto 6½, Kerkez 8, Laimer 6½, Konsa 7½, Milenkovic 6½, Rashford 5½, Reijnders 6, Mbeumo 6, Koopmeiners 7, Coman 6½ |
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