| Round 16 | | Barnsley | 0 |
| | Half-time: | 0-1 | | Referee: | Boyeson 5 | | Attendance: | 22,999 | | Possession: | 52%-48% | | Total shots: | 14-9 | | MoM: | Simpson |
| | 3 González | | (4-3-3): Ten Rouwelaar 7, Simpson 7½, José Enrique 6½, Kruijs 7½, Pavón 7, Gerrard 6½, Fagan 6½, Reyes 7½, Ormerod 7, González 6½, Kamarà 6 | | West Ham United | 1 | 20 López |
| | (4-3-3): Kirkland 7, Emerton 7, Borrowdale 6½, Gallardo 7½, El Karkouri 7, Carsley 6, Butcher 6, López 6, Corradi 7, Diego Tristán 6, Henderson 6 | | Boston United | 1 | 48 Dempsey | | Half-time: | 0-1 | | Referee: | Stroud 5 | | Attendance: | 6,623 | | Possession: | 56%-44% | | Total shots: | 14-12 | | MoM: | Fernandes |
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| | (4-3-3): Lastùvka 6½, Ebondo 7½, Wood 7½, Jankovic 7, Leigertwood 6, Markov 6, Ifill 6½, Dempsey 6½, Webò 7, Montillo 6, Pandev 7½ | | Aston Villa | 1 | 37 Zurawski | | 12 Hughes, 89 Zurawski | | (4-3-3): Jones 6½, Ricksen 6½, Thatcher 7 (48 Degen 7), Fernandes 8, Knight 6½, Materazzi 6, Beckham 6, Hughes 5½, Charisteas 6½, McCarthy 6½, Zurawski 6½ | | Charlton Athletic | 1 | 9 Løvenkrands | | Half-time: | 1-0 | | Referee: | Singh 6½ | | Attendance: | 36,989 | | Possession: | 44%-56% | | Total shots: | 10-18 | | MoM: | Gilberto |
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| | (4-3-3): Itandje 7½, Rusol 7, Gilberto 7½, Giannakopoulos 7, Oleguer 7, Tomkins 6½, Sidwell 7, Robinho 7, Hulse 6½, Macken 5½, Løvenkrands 5½ | | Carlisle United | 0 |
| | 45+1 Henry | | (4-3-3): Pelizzoli 7½, Ooijer 7, Gardner 7, Henry 7, Mensah 7, Taylor 6½ (85 Jones 6), Rommedahl 6½, Bresciano 6½, Borgetti 6½, Gasbarroni 6, Phillips 5½ | | Leyton Orient | 2 | 22 Valdez, 86 Taiwo | | Half-time: | 1-0 | | Referee: | Booth 7 | | Attendance: | 13,665 | | Possession: | 58%-42% | | Total shots: | 20-8 | | MoM: | Gentner |
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| | (4-3-3): Zuberbühler 6½, Demel 8, Taiwo 6½, Gentner 8, Arzo 7, Wolf 6½, Serkan 7½, Karyaka 6½, Chamakh 7½, Reid 7, Valdez 6½ | | Ipswich Town | 1 | 65 Mancienne | | 15 Eduardo, 51 Eduardo | | (4-3-3): Green 7, Melchiot 6, Bromby 6½, Ireland 6, Mancienne 6½, Eduardo 6, Gutiérrez 6½ (87 Briand 6), Duff 6½, Carew 7, Delap 6½, Absalonsen 6 | | Luton Town | 2 | 64 Toni, 77 Nani | | Half-time: | 0-1 | | Referee: | Vurens 7 | | Attendance: | 26,687 | | Possession: | 46%-54% | | Total shots: | 11-11 | | MoM: | Parejo |
| | 23 Cahais | | (4-3-3): Sippel 7, Westermann 6, Cahais 6½, Jenas 7 (78 Parejo 8), Dawson 8, Jorge Andrade 6½, Kuyt 7, Nani 6 (78 Rolfes 6), Toni 7, Mancini 6½, Raúl 5½ | | Bury | 1 | 30 Jerez |
| | (4-3-3): Steele 7½, Jerez 8, Distin 6½, Pedretti 8, Edwards 7, João Pereira 6, Stead 7 (70 Thornton 6), Bruno Gama 7, Pogrebnyak 6, Cousin 5½, Morrison 6 | | Middlesbrough | 1 | 72 Rufete | | Half-time: | 0-0 | | Referee: | Freestone 7 | | Attendance: | 39,888 | | Possession: | 44%-56% | | Total shots: | 10-8 | | MoM: | Raúl Bravo | | TV: | live |
| | 64 Bouma | | (4-3-3): De Sanctis 7½, Zaccardo 6½ (63 Hobbs 7), Favalli 7½, Aimar 7, Legrottaglie 7, Bouma 6, Font 6, Grønkjær 6½, Pizarro 6½, Rufete 7, Saviola 6 | | Plymouth Argyle | 0 |
| | 57 Todd | | (4-3-3): Dudek 7½, Dunne 7, Raúl Bravo 8, Sergio 7 (62 Viðarsson 7), Upson 7, Boumsong 6½, Barnetta 7, Kewell 6½ (48 Todd 6), Santa Cruz 8, Wilhelmsson 5½, Semak 6½ | | Millwall | 1 | 20 Kranjcar | | Half-time: | 1-1 | | Referee: | Woolmer 5½ | | Attendance: | 20,038 | | Possession: | 60%-40% | | Total shots: | 16-5 | | MoM: | Arbeloa |
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| | (4-3-3): Butina 6½, Arbeloa 8½, Silvestre 7½, Cahill 8, Craddock 6½, Simic 6½, Lurling 7, Kranjcar 7½, Kitson 6½ (69 Edman 7½), Meghni 6, Tuncay 7 | | Crystal Palace | 1 | 40 Øren | | 5 Kyrgiakos | | (4-3-3): Rüstü 6½, Burdisso 7, Ball 6½, Baraja 7, Kovác 6½, Kyrgiakos 5½, Davis 6½, Aliadière 5½, Øren 7, Diarra 6, Di Vaio 6½ | | Peterborough United | 1 | 26 Jarvis | | Half-time: | 1-2 | | Referee: | Wright 6 | | Attendance: | 15,254 | | Possession: | 53%-47% | | Total shots: | 17-11 | | MoM: | Verbír |
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| | (4-3-3): Harper 6½, Cuéllar 7, Van Der Heyden 7, Huggel 7, Nelsen 8, Karhan 6½, Verbír 8, Jarvis 7, Hashemian 7, Nørregaard 6, De Smet 5½ | | Hull City | 2 | 18 Sennikov, 43 Di Canio |
| | (4-3-3): Jääskeläinen 6, Rullo 6½, Sennikov 7½, Di Canio 7½, Edmílson 7, Shackell 6, Rosales 6½, Jørgensen 7, Beattie 7, Valerón 5½, Delgado 6 | | Port Vale | 2 | 22 Piquionne, 75 Babic | | Half-time: | 1-2 | | Referee: | Scott 7½ | | Attendance: | 24,193 | | Possession: | 46%-54% | | Total shots: | 13-15 | | MoM: | Van Damme |
| | 39 Vandenbergh | | (4-3-3): Verbist 6½, Volz 6 (52 Butterfield 6½), Van Damme 8½, Vandenbergh 7½, Wendel 8½, Riggott 6½, Buffel 7, Babic 7, Piquionne 7, Kanu 6½, Bozhinov 6½ | | Rushden & Diamonds | 2 | 14 Tikhonov, 32og Riggott |
| | (4-3-3): Lobont 6½, Zvoko 7, Armand 7½, Hughes 8, Diagne-Faye 7, Pogatetz 5½, Stock 6, Tikhonov 7, Samaras 7½, Sharp 7 (61 Elliott 6), Maccarone 6 | | Reading | 1 | 83 Zamora | | Half-time: | 0-0 | | Referee: | Bratt 6½ | | Attendance: | 34,161 | | Possession: | 42%-58% | | Total shots: | 11-11 | | MoM: | Melli |
| | 28 Zamora, 31 Doyle | | (4-3-3): Aranzubía 6½, Sagna 7½, Bertrand 7, Rothen 7½, Vlaar 7, Ricardo Rocha 7, Diana 7, Solari 6½ (82 Seitaridis 6), Zamora 7½, Doyle 5½, Shevchenko 7½ | | Birmingham City | 1 | 54 Jimenez |
| | (4-3-3): Oakes 7, Melli 8, Haas 6, Wichniarek 7½, Cláudio Caçapa 6½, Tonge 6, Jimenez 7, Malbranque 7½, Sonck 7, Roberts 6, Yakin 7 | | Scunthorpe United | 0 |
| | Half-time: | 0-2 | | Referee: | Russell 6½ | | Attendance: | 15,161 | | Possession: | 42%-58% | | Total shots: | 11-11 | | MoM: | Grella |
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| | (4-3-3): Proto 6, Antonsson 7, Järdler 6½, Donadel 8, Scharner 7, Faty 5½, Osman 6½, George 7½, Morison 5½, Reid 6½, Bowyer 5½ | | QPR | 2 | 33 Okkas, 43 Alex | | 1 Asamoah, 14 Alex, 54 Okkas | | (4-3-3): Andersen 6½, Colin 8, Vignal 6 (80 Hammell 6), Grella 8, Mokoena 8, Hogg 6, Asamoah 8, Alex 7½, Okkas 7, Kerr 7½, Bodipo 6 | | Swansea City | 3 | 15 Riera, 29 Keko, 68 Saha | | Half-time: | 2-0 | | Referee: | Whitestone 6½ | | Attendance: | 10,361 | | Possession: | 44%-56% | | Total shots: | 10-8 | | MoM: | Richardson | | TV: | highlights |
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| | (4-3-3): Stekelenburg 6½, Paulo Ferreira 7, Warnock 7, Richardson 8, Cris 7, Bassong 5½ (68 Metzelder 7½), Brown 7½, Riera 7½, Saha 7, Pennant 6½, Keko 5½ | | Manchester City | 1 | 67 Friedrich |
| | (4-3-3): Abbondanzieri 7½, Friedrich 7½, Mathijsen 8, Smith 7, Perea 6½, Van Buyten 6, Boulahrouz 7, Cardozo 6½, Morimoto 7, Foti 6½, Júlio Baptista 6½ | | Round 17 | | Aston Villa | 0 |
| | Half-time: | 0-1 | | Referee: | Moss 7 | | Attendance: | 27,223 | | Possession: | 48%-52% | | Total shots: | 16-14 | | MoM: | Craddock |
| | 33 Ricksen, 83 Hughes | | (4-3-3): Jones 5½, Ricksen 7 (63 Degen 6), Thatcher 6½, Fernandes 7½, Knight 6½, Materazzi 6½, Beckham 7½, Hughes 5½, Charisteas 7, McCarthy 6, Zurawski 5½ | | Millwall | 2 | 43 Kranjcar, 51 Kranjcar |
| | (4-3-3): Butina 6½, Arbeloa 7½, Silvestre 7, Cahill 7½, Craddock 7½, Simic 6, Lurling 7½, Kranjcar 7, Kitson 7 (69 Beevers 6½), Meghni 6½, Tuncay 7½ | | Birmingham City | 2 | 34 Malbranque, 57 Malbranque | | Half-time: | 1-0 | | Referee: | Webster 6 | | Attendance: | 29,893 | | Possession: | 51%-49% | | Total shots: | 13-6 | | MoM: | Verbist |
| | 13 Roberts, 77 Malbranque | | (4-3-3): Oakes 7, Melli 7½, Haas 7, Wichniarek 7, Cláudio Caçapa 6 (50 Igoe 6½), Tonge 6, Jimenez 7, Malbranque 7½, Roberts 7 (79 Smart 6), Sonck 6, Yakin 7 | | Port Vale | 0 |
| | 30 Babic | | (4-3-3): Verbist 8, Volz 6½ (52 Butterfield 7), Van Damme 6½, Vandenbergh 7, Wendel 7, Riggott 5½, Buffel 7½, Babic 6½, Piquionne 7, Kanu 5½, Bozhinov 5½ | | Bury | 0 |
| | Half-time: | 0-0 | | Referee: | Bates 5½ | | Attendance: | 11,760 | | Possession: | 41%-59% | | Total shots: | 7-15 | | MoM: | George |
| | 30 Stead, 38 Pedretti, 45+1 Edwards, 79 Thornton | | (4-3-3): Steele 7½, Jerez 8, Distin 7½, Pedretti 7½, Edwards 6½, João Pereira 6, Stead 7 (70 Thornton 6), Bruno Gama 6½, Pogrebnyak 7, Cousin 5½, Morrison 5½ | | Scunthorpe United | 1 | 88 Scharner | | 53 Vennegoor Of Hesselink | | (4-3-3): Proto 6½, Antonsson 7½, Järdler 7½, Donadel 7 (88 Muri 6), Scharner 7½, Faty 6½, Osman 8, George 8, Vennegoor Of Hesselink 7½, Reid 7, Bowyer 5½ | | Carlisle United | 2 | 19 Bresciano, 40 Bresciano | | Half-time: | 2-0 | | Referee: | Penn 8 | | Attendance: | 22,572 | | Possession: | 57%-43% | | Total shots: | 10-11 | | MoM: | Borgetti |
| | 69 Gasbarroni | | (4-3-3): Pelizzoli 7, Ooijer 7, Gardner 7, Henry 6½, Mensah 7, Taylor 6½, Rommedahl 7½, Bresciano 7½, Borgetti 7½, Gasbarroni 6, Phillips 6 | | Luton Town | 1 | 57 Toni | | 44 Jenas | | (4-3-3): Sippel 6½, Westermann 7½, Cahais 7 (55 Scannell 6), Jenas 6½, Dawson 7 (84 Parejo 6), Jorge Andrade 5½, Kuyt 7, Nani 6½, Toni 6½, Javi Martínez 6, Raúl 6 | | Crystal Palace | 0 |
| | Half-time: | 0-0 | | Referee: | Taylor 6½ | | Attendance: | 26,265 | | Possession: | 48%-52% | | Total shots: | 8-17 | | MoM: | Davis |
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| | (4-3-3): Rüstü 6, Burdisso 7, Ball 6½, Baraja 6, Kovác 7, Kyrgiakos 6, Davis 8, Aliadière 6, Øren 7, Diarra 6, Di Vaio 6 | | Middlesbrough | 2 | 68 Rufete, 75 Hobbs | | 39 Bouma | | (4-3-3): De Sanctis 6½, Zaccardo 7 (63 Hobbs 7½), Favalli 6½, Aimar 7, Legrottaglie 6, Bouma 7½, Font 7½, Grønkjær 7½, Pizarro 7½, Rufete 7, Saviola 5½ | | Hull City | 2 | 7 Beattie, 41 Jørgensen | | Half-time: | 2-0 | | Referee: | Thorpe 7 | | Attendance: | 25,130 | | Possession: | 53%-47% | | Total shots: | 16-12 | | MoM: | Ten Rouwelaar |
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| | (4-3-3): Jääskeläinen 6½, Rullo 7, Sennikov 7½, Di Canio 7, Edmílson 6½, Shackell 6, Rosales 7, Jørgensen 6½, Beattie 7½, Valerón 7, Delgado 6 | | Barnsley | 1 | 87 González | | 3 Gerrard | | (4-3-3): Ten Rouwelaar 8, Simpson 6½, José Enrique 6½, Kruijs 7½, Pavón 7½, Gerrard 7 (51 Berson 6), Fagan 7, Reyes 6½, Niyazi Serhat 6, González 6, Kamarà 5½ | | Ipswich Town | 0 |
| | Half-time: | 0-1 | | Referee: | Salisbury 5½ | | Attendance: | 30,099 | | Possession: | 51%-49% | | Total shots: | 14-9 | | MoM: | Warnock |
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| | (4-3-3): Green 6½, Melchiot 7½, Bromby 6½, Ireland 7½, Mancienne 7, Eduardo 6, Gutiérrez 7 (75 Briand 6), Duff 6½, Carew 6½, Delap 7, Absalonsen 6 | | Swansea City | 1 | 4 Cris |
| | (4-3-3): Stekelenburg 7, Paulo Ferreira 6, Warnock 8, Richardson 6½, Cris 7½, Bassong 6½ (68 Metzelder 6½), Brown 7½, Riera 6½, Saha 7, Pennant 6, Keko 5½ | | Manchester City | 0 |
| | Half-time: | 0-1 | | Referee: | Galanopoulos 6½ | | Attendance: | 34,024 | | Possession: | 44%-56% | | Total shots: | 10-21 | | MoM: | Bertrand |
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| | (4-3-3): Abbondanzieri 6½, Friedrich 6½, Mathijsen 6, Smith 7, Perea 7, Van Buyten 6½, Boulahrouz 6½, Cardozo 6½, Morimoto 7, Foti 6, Júlio Baptista 7 | | Reading | 1 | 35 Solari |
| | (4-3-3): Aranzubía 7½, Sagna 6, Bertrand 8, Rothen 7½, Vlaar 7, Ricardo Rocha 6½, Diana 7½, Solari 7½, Zamora 7, Doyle 6, Shevchenko 6 | | QPR | 1 | 13 Asamoah | | Half-time: | 1-1 | | Referee: | Mathieson 7 | | Attendance: | 19,035 | | Possession: | 60%-40% | | Total shots: | 21-17 | | MoM: | Mokoena |
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| | (4-3-3): Andersen 5½, Colin 8, Vignal 6, Grella 6½ (83 Vincent 6), Mokoena 8, Hogg 6½, Asamoah 7, Alex 7½, Okkas 8, Kerr 6½, Bodipo 7 | | Charlton Athletic | 5 | 6 Oleguer, 57 Sidwell, 66 Robinho, 84 Sidwell, 90+1 Sidwell |
| | (4-3-3): Itandje 5½, Rusol 7, Gilberto 7, Giannakopoulos 6½, Oleguer 6½, Tomkins 6, Sidwell 7½, Robinho 7, Hulse 6½, Macken 5½, Løvenkrands 5½ | | Rushden & Diamonds | 2 | 13 Samaras, 40og Wood | | Half-time: | 2-1 | | Referee: | Williamson 5½ | | Attendance: | 6,526 | | Possession: | 51%-49% | | Total shots: | 15-13 | | MoM: | Hughes |
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| | (4-3-3): Lobont 6½, Zvoko 7, Armand 7, Hughes 8, Diagne-Faye 6 (78 Taylor 6), Pogatetz 6½, Stock 7, Tikhonov 7, Samaras 7½, Sharp 6, Maccarone 7 | | Boston United | 2 | 38 Montillo, 48 Ifill |
| | (4-3-3): Lastùvka 6½, Ebondo 7, Wood 7½, Jankovic 7, Leigertwood 7, Schut 6½, Ifill 7, Dempsey 6½, Webò 7, Montillo 6, Pandev 6 | | West Ham United | 1 | 68 Corradi | | Half-time: | 0-0 | | Referee: | Miller 7 | | Attendance: | 28,824 | | Possession: | 50%-50% | | Total shots: | 17-8 | | MoM: | Henderson |
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| | (4-3-3): Kirkland 7, Emerton 7, Borrowdale 6, Gallardo 7, El Karkouri 6½, Carsley 6½, Butcher 6, López 7½, Corradi 7½, Diego Tristán 5½, Henderson 7½ | | Peterborough United | 0 |
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| | (4-3-3): Harper 7, Cuéllar 7½, Van Der Heyden 7½, Huggel 7, Nelsen 7½, Karhan 6½, Verbír 7½, Jarvis 6½, Hashemian 7, Nørregaard 7, De Smet 6 |
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